摘要
A detailed chemical study on the Hainan soft coral Sinularia crass has resulted in the isolation and characterization of eleven cas-bane-type diterpenoids,named sinucrassins A-K(1-11),along with six known related ones(12-17).Their structures were elucidated by extensive spectroscopic analyses and comparison with the reported data.The absolute configurations of new compounds were determi ned by the X-ray diffracti on analysis and computer-assisted structural elucidati on in eluding 13C NMR data calculati on and time-dependent density functional theory/electronic circular dichroism calculation.
基金
supported by the National Natural Science Foundation of China(No.81991521)
the National Key Research and Development Program of China(No.2018YFC0310903)
the SKLDR/SIMM Project(No.SIMM2103ZZ-06)。
