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单细胞转录组测序在人心血管疾病中的应用 被引量:1

Update on the value and application of single-cell RNA sequencing in human cardiovascular diseases
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摘要 近年来转录组测序技术实现了从低通量到高通量的快速发展。但传统的转录组测序技术局限于群体细胞基因表达平均水平,忽视了细胞间的异质性,而单细胞转录组测序可在单个细胞水平得到基因表达图谱,在分析细胞异质性、寻找心血管疾病新的诊断和治疗靶点以及促进心脏再生中发挥重要作用。该文综述了单细胞转录组测序在心血管疾病领域应用的研究进展。
作者 涂丁元 徐强 宋晓伟 赵仙先 Tu Dingyuan;Xu Qiang;Song Xiaowei;Zhao Xianxian(Department of Cardiology,Changhai Hospital,Naval Medical University,Shanghai 200433,China)
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2021年第10期1033-1036,共4页 Chinese Journal of Cardiology
基金 国家自然科学基金(81570208)。
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