能量及宏量营养素摄入与女童初潮年龄关联的前瞻性研究

A prospective study on the associations between dietary intakes of energy and macronutrients before menarche and age at menarche among girls

利用中国居民健康与营养调查(CHNS)数据,选取1989—2015年间具有初潮信息且在初潮发生前1~5年内至少参与了一次膳食调查的840名6~15岁女童作为研究对象。840名研究对象的年龄M(P_(25),P_(75))为10(9,11)岁,初潮年龄M(P_(25),P_(75))为13(12,14)岁。调整出生年代、居住地、体重指数Z评分、体力活动水平、家庭人均年收入后,初潮前脂肪日均摄入量每增加10 g,初潮年龄平均提前0.036(95%CI:-0.068,-0.004)岁;初潮前脂肪日均供能比每增加1%,初潮年龄平均提前0.008(95%CI:-0.014,-0.001)岁。

Based on the data from China Health and Nutrition Survey(CHNS),840 girls aged 6-15 years who had information about menarche and participated in dietary survey at least once within 1-5 years before onset of menarche between 1989 and 2015 were included in the study.The median age at baseline of the 840 participants was 10(9,11)years.The median age at menarche of the participants was 13(12,14)years.After adjusting for the age of birth,place of residence,body mass index Z-score,physical activity level and annual household income per capita,the average age of menarche was advanced by 0.036(95%CI:-0.068,-0.004)years for every 10 g increase in daily fat intake before menarche.The average age at menarche was 0.008(95%CI:-0.014,-0.001)years earlier for every 1%increase in the daily energy supply ratio of fat before menarche.