摘要
Sulfoxonium ylides as carbene precursors couple smoothly with thioureas in the presence of 5 mol% of rhodium(Ⅱ) acetate dimmer via carbenoid insertion to afford the corresponding 2-aminothiazoles with high chemoselectivity,providing a facile and efficient approach to access a variety of 2-aminothiazole derivatives with good functional groups tolerance.
基金
support from the National Natural Science Foundation of China (Nos.81373259 and 81573286)
Sichuan Science and Technology Program (Nos.2020YJ0221 and 2018JY0537)。
