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Preparation of selenofunctionalized heterocycles via iodosobenzene-mediated intramolecular selenocyclizations of olefins with diselenides

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摘要 An intramolecular selenocyclizations of olefins mediated by a commercially available hypervalent iodine(Ⅲ) reagent,PhIO,was developed.This method provided access to a wide range of selenenylated heterocycles under ambient conditions.The striking advantages of this protocol over all previous methods include mild reaction conditions,easy operation,good yields,high levels of functional group compatibility,large-scale application and suitability for the late-stage functionalization of complex molecules of biological importance.
机构地区 School of Pharmacy
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第8期2587-2591,共5页 中国化学快报(英文版)
基金 supported by the Natural Science Foundation of Jiangsu Province (No.BK20170439) Science and Technology Plan Projects of Nantong (Nos.JC2019102 and JC2020072)。
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