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诺氟沙星与左氧氟沙星治疗细菌性结膜炎的临床观察 被引量:1

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摘要 目的观察诺氟沙星与左氧氟沙星治疗细菌性结膜炎的临床效果。方法82例细菌性结膜炎患者按随机数表法分为对照组和试验组,每组41例。对照组予以诺氟沙星滴注患眼,每次2滴,1日3~5次。试验组采用左氧氟沙星滴注患眼,每次2滴,1日3~5次,两组均持续治疗7 d。比较两组临床疗效,细菌清除情况,眼表状况,和不良反应发生情况。结果试验组和对照组有效率分别92.68%(38/41)和75.61%(31/41),细菌清除率分别为90.24%(37/41)和73.18%(30/41),比较有统计学差异(P<0.05)。治疗后,试验组和对照组泪膜破裂时间(BUT)分别为(8.51±0.88)和(7.70±1.46)s,基础泪液分泌试验(SIt)分别为(9.18±0.74)和(7.58±0.96)s,比较有统计学差异(P<0.05)。两组不良反应以眼部烧灼、眼部瘙痒为主,对照组和试验组不良反应发生率分别为9.76%(4/41)和12.19%(5/41),比较无统计学差异(P>0.05)。结论左氧氟沙星治疗细菌性结膜炎的效果优于诺氟沙星,促进细菌清除,改善眼表状态。
出处 《海峡药学》 2021年第10期116-118,共3页 Strait Pharmaceutical Journal
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