AngioJet血栓清除术治疗急性深静脉血栓形成后急性肾损伤的影响因素分析

Influencing factors of acute kidney injury after AngioJet thrombectomy in patients with acute deep venous thrombosis

目的探讨AngioJet血栓清除术治疗急性深静脉血栓形成(DVT)后急性肾损伤(AKI)的影响因素。方法收集2020年1月至2020年12月在北京积水潭医院行AngioJet血栓清除术治疗的82例急性DVT患者的临床资料,根据AngioJet血栓清除术后是否发生AKI情况进行分组为AKI组(n=13)和非AKI组(n=69)。术后发生AKI的影响因素分析采用Logistic回归分析。结果单因素分析结果显示,AKI组合并高血压患者比例高于非AKI组患者,血栓清除时间长于非AKI组患者,术中对比剂用量多于非AKI组患者,差异有统计学意义(P<0.05)。多因素分析结果显示,合并高血压、术中对比剂用量>125 ml是术后发生AKI的危险因素。结论合并高血压和术中对比剂用量是AngioJet血栓清除术治疗DVT后发生AKI的危险因素,高血压患者应减少对比剂用量。

Objective To evaluate the influencing factors of acute kidney injury(AKI)after AngioJet thrombectomy in patients with acute deep venous thrombosis(DVT).Method The clinical data of 82 patients with acute DVT treated with AngioJet thrombectomy in Beijing Jishuitan Hospital from January 2020 to December 2020 were collected and divided into AKI group(n=13)and non-AKI group(n=69)according to the incidence of AKI after AngioJet thrombectomy.Logistic regression analysis was used to analyze the influencing factors of postoperative AKI.Result Univariate analysis showed that the proportion of patients with hypertension in AKI group was higher than that in non AKI group,the thrombus clearance time was longer than that in non AKI group,and the intraoperative contrast agent dosage was more than that in non AKI group(P<0.05).Multivariate Logistic regression analysis showed that concomitant hypertension and contrast medium dose>125 ml were independent risk factors for postoperative AKI.Conclusion Concomitant hypertension and contrast medium dose are independent risk factors for AKI after AngioJet thrombectomy in patients with acute DVT and patients with hypertension should minimize the use of contrast medium dose.