经会阴前列腺12+x针穿刺活检中不同穿刺部位前列腺癌检出率比较

Comparison of the Detection Rate of Prostate Cancer in Different Puncture Sites in Perineal Prostate 12+x Needle Puncture

目的研究经会阴前列腺12+x针穿刺活检中不同穿刺部位前列腺癌的检出率。方法选取2019年1月-2020年10月我院收治的78例疑似前列腺癌患者为研究对象,患者均在超声引导下经会阴进行前列腺12+x针穿刺活检,观察经会阴前列腺12+x针穿刺活检阳性率,并比较良恶性前列腺肿瘤前列腺特异性抗原(PSA)水平和体积及不同PSA水平和不同体积下12+x针不同穿刺部位前列腺癌检出率。结果78例疑似前列腺癌患者中,经病理学检查证实确诊35例前列腺癌,12+x针穿刺活检阳性率为44.87%(35/78);前列腺癌患者PSA水平高于良性前列腺增生,体积小于良性前列腺增生,差异有统计学意义(P<0.05)。不同PSA水平下不同位置前列腺癌检出率比较,差异有统计学意义(P<0.05),且随PSA水平降低,检出率也随之降低;相同PSA水平下,不同位置穿刺部位前列腺癌阳性检出率比较,差异无统计学意义(P>0.05)。不同体积下不同位置前列腺癌检出率比较,差异有统计学意义(P<0.05),且随体积的减小,检出率随之升高;相同体积下,不同位置穿刺部位前列腺癌阳性检出率比较,差异无统计学意义(P>0.05)。结论经会阴前列腺12+x针穿刺活检是诊断前列腺癌有效可行的方法,相同血清PSA水平、体积下不同穿刺部位阳性检出率基本一致,而不同体积、PSA水平阳性检出率存在差异。因此,在前列腺穿刺活检前应充分考虑体积、PSA水平,以获得更满意的穿刺和诊断结果。

Objective To study the detection rate of prostate cancer at different puncture sites in perineal prostate 12+x needle puncture.Methods A total of 78 patients with suspected prostate cancer admitted to our hospital from January 2019 to October 2020 were selected as the research objects.All patients underwent ultrasound-guided Perineal prostate 12+x needle puncture of the prostate.The positive rate of transperineal 12+x needle biopsy of the prostate was observed,and the prostate specific antigen(PSA)level and volume of benign and malignant prostate tumors and the detection rate of prostate cancer at different puncture sites of 12+x needles under different PSA levels and different volumes were compared.Results Among 78 patients with suspected prostate cancer,35 cases were confirmed by pathological examination,and the positive rate of 12+x needle biopsy was 44.87%(35/78).The PSA level of prostate cancer patients was higher than that of benign prostatic hyperplasia,and the volume was smaller than that of benign prostatic hyperplasia,the difference was statistically significant(P<0.05).The detection rates of prostate cancer at different locations under different PSA levels were statistically significant(P<0.05),and the detection rate decreased with the decrease of PSA level;under the same PSA level,there was no significant difference in the positive detection rate of prostate cancer at different puncture sites(P>0.05).There was significant difference in the detection rate of prostate cancer at different locations under different volumes(P<0.05),and the detection rate increased with the decrease of volume;under the same volume,there was no significant difference in the positive detection rate of prostate cancer at different puncture sites(P>0.05).Conclusion 12+x transperineal prostate needle biopsy is an effective and feasible method for the diagnosis of prostate cancer.The positive detection rates at different puncture sites are basically the same at the same serum PSA level and volume,while the positive detection rates at different volumes and PSA levels are different.Therefore,volume and PSA level should be fully considered before prostate biopsy to obtain more satisfactory puncture and diagnosis results.