摘要
Polymorphonuclear neutrophils(PMNs)possess multiple distinct types of cytoplasmic granules:secondary granules,tertiary granules,and azurophil granules[1].It has been suggested that PMN degranulation is controlled by exocytotic machinery comprising membrane-specific SNARE proteins,soluble N-ethylmaleimide sensitive factor(NSF)and soluble NSF-attaching proteins[2].
基金
This work was supported by grants from the Ministry of Science and Technology of China(2018YFA0507100)
the National Natural Science Foundation of China(31670917,31770981,32000634,and 81803626)
the Natural Science Foundation of Jiangsu Province(BK20180556)
the fellowship of China Postdoctoral Science Foundation(2018M630642).