间歇和持续蓝光治疗新生儿黄疸的疗效

Efficacy of Intermittent and Continuous Blue Light in the Treatment of Neonatal Jaundice

目的研究间歇蓝光照射与持续蓝光照射用于治疗新生儿黄疸的临床价值。方法方便选取该院在2019年9月—2020年10月期间内收治的黄疸新生儿90例作为研究对象,用随机数字表法分组,每组45例。两组患儿均接受蓝光照射治疗,对照组的治疗模式是持续蓝光照射治疗,而观察组的治疗模式是间歇蓝光照射治疗,比较两种不同治疗方法在临床疗效、血清胆红素改善情况、临床症状改善时间以及治疗安全性方面的异同。结果经对比临床总有效率,观察组的治疗总有效率(95.56%)较对照组(82.22%)相比相对较高,差异有统计学意义(χ^(2)=4.050,P<0.05);治疗后两组的血清胆红素水平较治疗前相比均显著降低,而观察组治疗后的血清胆红素水平(205.15±4.13)μmol/L和对照组相比相对较低,组间差异有统计学意义(P<0.05);观察组患儿的症状消失时间、胆红素恢复正常时间、治疗时间较对照组相比均相对较短,组间差异有统计学意义(t=46.178、15.669、8.255,P<0.05);观察组治疗期间的不良反应发生率(6.66%)和对照组(31.11%)相比相对较低,组间差异有统计学意义(χ^(2)=8.775,P<0.05)。结论在新生儿黄疸的临床治疗上,间歇蓝光照射治疗的效果优于持续蓝光照射,无论是在治疗有效性还是在治疗安全性上均存在一定的优势,同时可在短时间内改善患儿的临床症状,缩短治疗时间,降低胆红素水平,总体效果理想,因此,具备临床应用和推广的价值。

Objective To study the clinical value of intermittent blue light irradiation and continuous blue light irradiation in the treatment of neonatal jaundice.Methods Conveniently selected to 90 neonates with jaundice admitted in the hospital between September 2019 and October 2020 were taken as the main research objects,and were grouped by random number table,with 45 cases in each group Two groups of children received blue light irradiation treatment.The treatment mode of the control group was continuous blue light irradiation treatment,while the treatment mode of the observation group was intermittent blue light irradiation treatment.The clinical efficacy,serum bilirubin improvement,and improvement of the two different treatment methods of similarities and differences in clinical symptoms improvement time and treatment safety were compared.Results The total effective rate of the observation group(95.56%)was higher than that of the control group(82.22%),and the difference was statistically significant(χ^(2)=4.050,P<0.05);after treatment,the serum bilirubin level in the two groups was significantly lower than that before treatment,while the serum bilirubin level in the observation group was(205.15±4.13)μmol/L lower than that in the control group,and the difference was statistically significant(P<0.05);the symptoms disappeared time,the normal time of bilirubin and the treatment time in the observation group were relatively shorter than those in the control group,and the difference between the two groups was statistically significant(t=46.178,15.669,8.255,P<0.05);the incidence of adverse reactions during treatment in the observation group(6.66%)was relatively lower than that in the control group(31.11%),and the difference between the two groups was statistically significant(χ^(2)=8.775,P<0.05).Conclusion In the clinical treatment of neonatal jaundice,the effect of intermittent blue light irradiation is better than that of continuous blue light irradiation.There are certain advantages in both the therapeutic effectiveness and the safety of the treatment,and it can improve the children’s health in a short time.Clinical symptoms,shorten the treatment time,reduce the level of bilirubin,and the overall effect is ideal.Therefore,it has the value of clinical application and promotion.