康复新液在大肠息肉切除术后的临床疗效分析

Clinical Observation of Kangfuxin Liquid after Resection of Colorectal Polypectomy

目的观察康复新液在大肠息肉切除术后患者的临床疗效。方法便利选取2018年7月—2020年6月期间在漳州市中医院脾胃病科住院的符合纳入标准的大肠息肉患者75例,随机分为研究组38例、对照组37例。对照组予常规内镜下大肠息肉切除术治疗,术后予止血、补液等治疗。研究组在对照组治疗基础上,在内镜治疗过程中于创面喷洒康复新液50~100 mL左右,观察创面无明显渗血10 s后退镜。观察两组治疗后首次及1周后大便隐血情况,评价术后1周患者临床疗效,治疗后1个月复查肠镜观察黏膜修复情况。结果术后首次大便隐血情况比较,两组患者差异无统计学意义(χ^(2)=1.920,P=0.166);术后1周,研究组大便隐血阳性患者4例明显少于对照组的12例,差异有统计学意义(χ^(2)=5.361,P=0.021)。术后1周临床疗效比较,研究组总有效率为97.37%,显著高于对照组的78.38%,差异有统计学意义(χ^(2)=4.730,P=0.030)。术后1月复查电子肠镜:研究组肠道粘膜修复情况明显优于对照组,差异有统计学意义(Z=-2.739,P=0.006)。结论提示在内镜治疗过程中使用康复新液可减少出血,并改善患者临床疗效,促进创面修复愈合。

Objective To observe the clinical efficacy of Kangfuxin Liquid in patients after colorectal polypectomy.Methods Conveniently selected 75 patients with colorectal polyps who met the inclusion criteria in the Department of spleen and stomach disease of Zhangzhou hospital of traditional chinese medicine from July 2018 to June 2020 were randomly divided into study group(38 cases)and control group(37 cases).The control group was treated with conventional endoscopic colorectal polypectomy,followed by hemostasis and fluid supplementation.Based on the treatment of the controled by hemostasis and fluid supplementation.Based on the treatment of the control group,the study group sprayed about 50-100 mL of Kangfuxin liquid on the wound surface during the endoscopic treatment,observed that there was no obvious bleeding on the wound surface,and then retracted the mirror for 10 s.Observation of fecal occult blood at the first and one week after the operation of the two groups was conducted,and the clinical efficacy of the patients was evaluated at the first week after the operation.Electronic colonoscopy was performed one month after the operation to observe the repair and healing of intestinal mucosa after the resection of polyps under the colonoscope.Results There was no statistically significant difference in fecal occult blood between the two groups in the first postoperative session(χ^(2)=1.920,P=0.166).One week after operation,the number of patients with fecal occult blood positive four cases in the study group was significantly lower than that twelve cases in the control group,and the difference was statistically significant(χ^(2)=5.361,P=0.021).One week after operation,the total effective rate of the study group 97.37%was significantly higher than that of the control group 78.38%,and the difference was statistically significant(χ^(2)=4.730,P=0.030).Reexamination with electronic colonoscopy 1 month after surgery:the study group was significantly better than the control group in the repair and healing of intestinal mucosa,and the difference was statistically significant(Z=-2.739,P=0.006).Conclusion The use of kangfuxin in endoscopic therapy can reduce bleeding,improve the clinical efficacy of patients,and promote wound repair and healing.