中国居民2000—2019年因饮酒导致死亡及寿命年损失情况

Mortalities and years of life lost correlated to alcohol use among residents in China: 2000-2019

目的了解中国居民2000—2019年因饮酒导致的死亡及寿命年损失情况,为我国控酒工作的开展提供数据支持和政策依据。方法收集2019全球疾病负担研究(GBD 2019)中2000—2019年中国不同性别和年龄居民归因于饮酒的疾病别死亡及过早死亡损失寿命年(YLL)情况,采用平均年度变化百分比(AAPC)和年度变化百分比(APC)分析我国居民2000—2019年因饮酒导致的死亡及YLL变化趋势。结果中国居民因饮酒导致的死亡标化率和YLL标化率分别从2000年的35.30/10万和955.84/10万下降到2019年的26.98/10万和715.84/10万,我国居民2000—2019年因饮酒导致的死亡标化率和YLL标化率总体均呈下降趋势(均P<0.001);其中男性和女性居民因饮酒导致的死亡标化率分别从2000年的67.62/10万和7.52/10万下降到2019年的54.72/10万和4.44/10万,YLL标化率分别从2000年的1759.04/10万和166.69/10万下降到2019年的1370.77/10万和95.07/10万,我国男性和女性居民2000—2019年因饮酒导致的死亡标化率和YLL标化率总体均呈下降趋势(均P<0.001)。15~49岁居民因饮酒导致的传染性疾病和非传染性疾病死亡率分别从2000年的1.06/10万和9.17/10万下降到2019年的0.35/10万和8.38/10万,YLL率分别从2000年的53.15/10万和438.82/10万下降到2019年的17.02/10万和395.73/10万,我国15~49岁居民2000—2019年因饮酒导致的传染性疾病和非传染性疾病死亡率和YLL率总体均呈下降趋势(均P<0.001);50~69岁居民因饮酒导致的传染性疾病、非传染性疾病和伤害死亡率分别从2000年的6.10/10万、73.75/10万和5.49/10万下降到2019年的1.80/10万、52.61/10万和3.96/10万,YLL率分别从2000年的176.83/10万、2190.40/10万和171.03/10万下降到2019年的52.12/10万、1545.58/10万和122.00/10万,我国50~69岁居民2000—2019年因饮酒导致的传染性疾病、非传染性疾病和伤害死亡率和YLL率总体均呈下降趋势(均P<0.001);≥70岁居民因饮酒导致的传染性疾病和非传染性疾病死亡率分别从2000年的23.03/10万和195.45/10万下降到2019年的10.48/10万和174.27/10万,YLL率分别从2000年的346.01/10万和3004.96/10万下降到2019年的139.03/10万和2514.83/10万,我国≥70岁居民2000—2019年因饮酒导致的传染性疾病和非传染性疾病死亡率和YLL率总体均呈下降趋势(均P<0.001)。结论中国居民2000—2019年因饮酒导致的死亡标化率和YLL标化率总体均呈下降趋势,但15~49岁和≥70岁居民因饮酒导致的伤害死亡率和YLL率未见显著下降趋势。

Objective To examine the mortality and years of life lost(YLLs) induced by alcohol use in China from 2000 to 2019 and to provide evidences for making policy on the control of alcohol use. Methods The data on estimated age-, gender-and disease-specific mortalities and YLLs attributable to alcohol use during the years from 2000 to 2019 in China were extracted from the Global Burden of Disease(GBD) Study. Average annual change percentage(AAPC) and annual change percentage(APC) were used to analyze changing trend in the mortalities and YLL rate during the period.Results From 2000 to 2019, the standardized mortality rate(1/100 000) and YLL rate(1/100 000) attributable to alcohol drinking for Chinese residents decreased from 35.30 and 955.84 to 26.98 and 715.84, with a significant downward trend(both P < 0.001);for the male and female Chinese residents from 2000 to 2019, the standardized mortality rate decreased from 67.62 and 7.52 to 54.72 and 4.44 and the standardized rate of YLL decreased from 1 759.04 and 166.69 to 1 370.77 and95.07, respectively;all the rates showed a significant downward trend(all P < 0.001). Among the residents aged 15 – 49 years, significant decreases from 2000 to 2019 were observed in alcohol use-related mortality rate(from 1.06 and 9.17 to 0.35 and 8.38) and YLL rate(from 53.15 and 438.82 to 17.02 and 395.73) of infectious and non-communicable diseases(all P <0.001). Compared to those in 2000, significant decreases in 2019 were observed in alcohol use-related mortality rates(1.80 vs. 6.10, 52.61 vs. 73.75, and 3.96 vs. 5.49) and YLL rates(52.12 vs. 176.83, 1 545.58 vs. 2 190.40, and 122.00 vs. 171.03)of infectious diseases, non-communicable diseases, and injuries among the residents aged 50 – 69 years(P < 0.001 for all);while among the residents ≥ 70 years old, significant decreases were also observed in alcohol use-related mortality rates(10.48 vs. 23.03 and 174.27 vs. 195.45) and YLL rates(139.03 vs. 346.01 and 2 514.83 vs. 3 004.96) of communicable diseases and non-communicable diseases(all P < 0.001). Conclusion From 2000 to 2019, the alcohol drinking-related mortality rate and YLL rate decreased in Chinese residents 15 years old and above generally but there was no significant downward trend was observed in the alcohol drinking-related mortality rate and YLL of injuries among the residents aged15 – 49 years and the residents aged 70 years and above.