探讨多层螺旋CT诊断肺局灶性磨玻璃密度结节的临床价值

Exploring the Clinical Value of Multi-slice Spiral CT in the Diagnosis of Pulmonary Focal Ground Glass Density Nodules

目的评估多层螺旋CT诊断肺局灶性磨玻璃密度结节的临床价值。方法选取2019年8月—2021年6月该院收治的286例行肺局灶性磨玻璃密度结节治疗的患者作为该次研究对象,针对所有对象病历资料予以回顾性分析。依据病理学检测病灶性质,将对象均分为对照组(良性病变)和观察组(恶性病变),每组143例。两组对象均予以多层螺旋CT扫描诊断,对比分析两组对象CT特征及病灶变化情况。结果观察组病灶大小以分布情况以3 cm以上为主,对照组则以1~2.9 cm为主,差异有统计学意义(χ^(2)=13.619、15.234、29.924,P<0.05);且观察组病灶平均直径显著大于对照组,差异有统计学意义(t=-8.366,P<0.05);观察组病灶轮廓分布情况以不规则、圆形和分叶状为主,对照组则以斑片状、不规则为主,差异有统计学意义(χ^(2)=25.506、184.092、36.031、45.158,P<0.05);观察组对象病灶边缘分布情况以毛刺状、光整和毛糙为主,对照组则以模糊为主,差异有统计学意义(χ^(2)=129.208、41.184、37.304、21.504,P<0.05);观察组病灶密度分布情况以Ⅱ型、Ⅲ型为主,对照组则以Ⅰ型为主,差异有统计学意义(χ^(2)=286.000、122.980、71.188,P<0.05);且观察组支气管充气征也显著高于对照组,差异有统计学意义(χ^(2)=47.051,P<0.05)。结论在诊断肺局灶性磨玻璃密度结节疾病诊断中实施多层螺旋CT诊断能有效鉴别结节性质,提高临床诊断准确率,为临床诊疗提供有价值的依据。

Objective To evaluate the clinical value of multi-slice spiral CT in the diagnosis of focal ground glass density nodules in the lung.Methods 286 patients with focal ground glass density nodules of the lung treated in the hospital from August 2019 to June 2021 were selected as the subjects of this study,and the medical records of all subjects were analyzed retrospectively.According to the nature of lesions detected by pathology,the subjects were divided into control group(benign lesions)and observation group(malignant lesions),with 143 cases in each group.The two groups of subjects were diagnosed by multi-slice spiral CT scanning,and the CT characteristics and lesion changes of the two groups were compared and analyzed.Results The distribution of lesions in the observation group was more than 3 cm,while that in the control group was 1-2.9 cm,the difference were statistically significant(χ^(2)=13.619,15.234,29.924,P<0.05).The average diameter of lesions in the observation group was significantly larger than that in the control group,the difference was statistically significant(t=-8.366,P<0.05).The distribution of lesion contour in the observation group was irregular,round and lobulated,while in the control group was patchy and irregular,the difference were statistically significant(χ^(2)=25.506,184.092,36.031,45.158,P<0.05).The edge distribution of lesions in the observation group was mainly burr,smooth and rough,while in the control group was mainly fuzzy,the difference were statistically significant(χ^(2)=129.208,41.184,37.304,21.504,P<0.05).The distribution of lesion density in the observation group was mainly typeⅡand typeⅢ,while that in the control group was mainly typeⅠ,the difference were statistically significant(χ^(2)=286.000,122.980,71.188,P<0.05).The bronchial inflation sign in the observation group was also significantly higher than that in the control group,the difference was statistically significant(χ^(2)=47.051,P<0.05).Conclusion The implementation of multi-slice spiral CT in the diagnosis of focal pulmonary ground glass density nodules can effectively identify the nature of the nodules,improve the accuracy of clinical diagnosis,and provide a valuable basis for clinical diagnosis and treatment.