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降钙素原对肾移植术后患者感染的预测价值

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摘要 目的:分析降钙素原(PCT)对评估肾移植术后感染的预测价值和临床意义。方法:回顾性分析2017年6月—2020年6月96例肾移植术后患者的临床资料,根据临床病原体培养结果以及临床症状将其分为感染组46例和非感染组50例。对比分析两组PCT在术前和术后第1~7天的差异,应用工作特征曲线(ROC)分析PCT对肾移植术后第2~5天发生感染的预测效能。结果:感染组与非感染组术前PCT对比,差异无统计学意义(P>0.05)。但肾移植术后第1~7天,感染组的PCT整体趋势和峰值明显高于非感染组,其中术后第2~5天的对比,差异有统计学意义(P<0.05)。ROC曲线分析显示,肾移植术后第2~5天的ROC曲线下面积(AUC)分别为0.745、0.773、0.792、0.794,差异均有统计学意义(P<0.05)。结论:降钙素原(PCT)对肾移植术后出现感染有预测价值,它能指导临床及时有效的使用抗菌药物,一定程度上能预防严重感染的发生。
出处 《医学理论与实践》 2021年第22期3982-3984,共3页 The Journal of Medical Theory and Practice
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