院外规范化治疗对急性肺栓塞患者复发的影响

The Influence of Out-of-hospital Standardized Treatment on the Recurrence of Patients with Acute Pulmonary Embolism

目的急性肺栓塞患者通过院外规范化治疗,研究治疗效果以及影响价值。方法选取该院在2019年1月—2020年1月期间收治的100例急性肺栓塞的患者,以随机数表法作为分组原则,分成50例观察组和50例对照组,其中观察组的治疗方法为院外规范化治疗,对照组采取常规规范化治疗,比较两组患者的复发率、病死率、中断治疗率,比较两组患者的治疗前后的肺灌注缺损评分。结果观察组患者的复发率为8.0%(4/50),病死率为4.0%(2/50),中断治疗率为2.0%(1/50),对照组患者的复发率为24.0%(12/50),病死率为16.0%(8/50),中断治疗率为16.0%(8/50),差异有统计学意义(χ^(2)=4.762、4.000、4.396,P<0.05);观察组和对照组患者的治疗前肺灌注缺损评分比较,差异无统计学意义(P>0.05),观察组治疗4 d、治疗7 d、治疗30 d后的肺灌注缺损评分分别为(13.4±5.1)分、(11.5±5.0)分、(4.7±2.4)分,对照组治疗4 d、治疗7 d、治疗30 d后的患者的肺灌注缺损评分分别为(17.6±7.8)分、(15.6±6.6)分、(9.8±7.0)分,差异有统计学意义(t=3.187、3.501、4.873,P<0.05)。结论通过院外规范化治疗方法对急性肺栓塞患者进行治疗,复发率、病死率大大降低,影响价值较高。

Objective To study the treatment effect and impact value of patients with acute pulmonary embolism through standardized out-of-hospital treatment.Methods Selected 100 patients with acute pulmonary embolism admitted to the hospital from January 2019 to January 2020,used the random number table method as the grouping principle,divided into 50 cases in the observation group and 50 cases in the control group.The treatment method of the observation group was standardized out-of-hospital treatment,and the control group took conventional standardized treatment.The recurrence rate,case fatality rate,and treatment interruption rate of the two groups were compared,and the lung perfusion defect scores of the two groups were compared before and after treatment.Results In the observation group,the recurrence rate was 8.0%(4/50),the case fatality rate was 4.0%(2/50),and the treatment interruption rate was 2.0%(1/50).In the control group,the recurrence rate was 24.0%(12/50),the case fatality rate was 16.0%(8/50),and the treatment interruption rate was 16.0%(8/50),the difference were statistically significant(χ^(2)=4.762,4.000,4.396,P<0.05);comparison of lung perfusion defect scores between observation group and control group before treatment,the difference were not statistically significant(P>0.05),the lung perfusion defect scores of the observation group after 4 days of treatment,7 days of treatment,and 30 days of treatment were(13.4±5.1)points,(11.5±5.0)points,and(4.7±2.4)points,respectively.The lung perfusion defect scores of the patients in the control group after after 4 days of treatment,7 days of treatment and 30 days of treatment were(17.6±7.8)points,(15.6±6.6)points,(9.8±7.0)points,the difference were statistically significant(t=3.187,3.501,4.873,P<0.05).Conclusion The recurrence rate and case fatality rate of patients with acute pulmonary embolism are greatly reduced through standardized out-of-hospital treatment methods,and the impact value is high.