肠内营养支持时机对急性脑卒中患者肠道屏障功能及预后的影响

Effect of Enteral Nutrition Support Timing on Intestinal Barrier Function and Prognosis in Patients with Acute Stroke

目的:探讨分析肠内营养支持时机对急性脑卒中患者肠道屏障功能及预后的影响。方法:选取2020年8月至2021年4月在笔者医院接受治疗的100例急性脑卒中患者作为研究对象,将其随机分为四组:研究组、对照A组、对照B组、对照C组各25例。结果:四组中,研究组患者的血清白蛋白、lgM含量均处于最高水平,D-乳糖、血清DAO含量及NIHSS评分均处于最低水平(P<0.05)。和对照B组、对照C组相比,研究组的感染发生率明显更低(P<0.05)。结论:入院后24 h内是给予肠内营养支持的最佳时机,可以更有效促进患者肠道屏障功能恢复,改善营养状况和预后。

Objective:To investigate the effect of enteral nutrition support timing on intestinal barrier function and prognosis in patients with acute stroke. Methods:From August 2020 to April 2021,100 patients with acute stroke were selected and randomly divided into four groups:study group,control A group,control B group and control C group with 25 cases in each group. Results:In the four groups,the serum albumin and lgM levels in the study group were the highest,while the D-lactose,serum DAO content and NIHSS score were the lowest(P<0.05). The incidence of infection in the study group was significantly lower than that in the control B group and the control C group(P<0.05). Conclusion:No more than 24 h after admission is the best time to give enteral nutrition support,which can more effectively promote the recovery of intestinal barrier function and improve nutritional status and prognosis.