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中性粒细胞和白蛋白比值与急性心肌梗死的关系 被引量:3

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摘要 目的:比较急性心肌梗死(AMI)患者和对照组的中性粒细胞和白蛋白比值(NAR),探讨NAR与AMI的关系。方法:选择2019年1月至2019年12月于本院就诊的AMI患者119例,冠脉造影正常者58例为研究对象。比较NAR在AMI患者和对照组中的差异。用ROC曲线分析NAR对AMI的诊断价值。分析NAR与肌钙蛋白T(cTnT)、肌钙蛋白I(cTnI)、肌酸激酶同工酶(CKMB)的相关性。分析NAR在重度心衰组(Killip≥3)和非重度心衰组(Killip<3)中的差异。结果:AMI组中的中性粒细胞、NLR、PLR、NAR和PAR高于对照组,差异具有统计学意义(P<0.05)。AMI组中的淋巴细胞和白蛋白低于对照组,差异具有统计学意义(P<0.05)。ROC分析结果显示NAR的AUC值明显高于NLR、PLR、PAR。其中,NAR的最佳cut off值为0.13,其对应的约登指数为0.840,敏感性为85.7%,特异性为98.2%。NAR与CTNT呈正相关。重度心衰组的NLR、NAR、CKMB、cTnT和cTnI明显高于非重度心衰组,差异具有统计学意义(P<0.05)。结论:NAR在AMI患者及重度心衰AMI患者中明显上调,对AMI及AMI发生重度心衰具有重要的诊断价值。
出处 《岭南急诊医学杂志》 2021年第5期519-521,共3页 Lingnan Journal of Emergency Medicine
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