基于认知性访谈的中文版患者报告结局测量信息系统焦虑和抑郁量表的研制

Development of anxiety and depression Scale in Chinese version of Patient Report Outcome Measurement Information System based on cognitive interview

目的检验翻译后的患者报告结局测量信息系统——焦虑、抑郁简表与源量表概念和语义是否等价并进行适当的文化调适。方法采用目的抽样,纳入上海市某三级甲等医院住院的肿瘤患者以及健康人群,通过质性研究方法中的认知性访谈技术,采用半结构式标准化问题探针开展3轮、共计20人的认知性访谈,了解受访者的作答过程,运用内容分析法进行资料分析,并根据访谈结果对中文版量表进行文化调适。结果第1轮访谈结果显示:受访者能够理解大多数条目,焦虑量表中有4个条目因“语法结构不完善、书面化语言”需要进行修饰;抑郁量表中有2个条目因“否定式”问题及直译所致的“污名化”而需要进行修改。第2轮访谈结果显示:受访者对焦虑量表汉化及修订后条目的语言理解与原问卷表达均一致,但对于抑郁量表的2个条目在经过第3轮认知性访谈修订后最终也达成一致。结论经认知性访谈、修改后,中文版患者报告结局测量信息系统——焦虑、抑郁简表与原版概念、语义等价,可用于下一步大样本测量学检验。

Objective To promote the conceptual and linguistic invariance of Chinese and English version of the anxiety and depression short forms of patient-reported outcomes measurement information system(PROMIS).Methods By purposive sampling,20 participants from a first-class hospital of Shanghai tumor patients and healthy population were recruited.Three rounds of cognitive interview were conducted.Content analysis was used to analyze data and cultural adaption was made based on interview results.Results The results of the first round of interviews showed that respondents could understand most of the items.Four items in the anxiety scale needed to be modified due to"imperfect grammatical structure and written language",and two items in the depression scale needed to be modified due to"negative"questions and"stigmatization"caused by literal translation.The results of the second round of interviews showed that interviewees'language understanding of the Chinese and revised items of the anxiety scale was consistent with the expression of the original questionnaire,but the two items of the depression scale were also agreed after the third round of cognitive interview.Conclusion Revised-Chinese version of the PROMIS-anxiety and depression short form is of invariance of concept and semantics with the original version,which is ready for measurement property test of large sample size.