胃镜下注射治疗消化性溃疡并急性上消化道出血的临床疗效分析

Analysis of clinical efficay of injection under gastroscope in the treatment of peptic ulcer complicated with acute upper gastrointestinal hemorrhage

目的探讨胃镜下注射治疗消化性溃疡并急性上消化道出血的临床疗效。方法66例消化性溃疡并急性上消化道出血患者,采用随机摸球法分为对照组和观察组,每组33例。对照组采用胃镜下对病灶部位进行药物喷洒治疗,观察组采用胃镜下对病灶部位进行药物注射治疗。比较两组患者治疗效果、治疗前后血红蛋白(Hb)水平、不良反应发生情况。结果观察组治疗总有效率97.0%高于对照组的66.7%,差异具有统计学意义(P<0.05)。治疗后,观察组Hb(108.56±19.76)g/L高于对照组的(96.17±15.88)g/L,差异具有统计学意义(P<0.05)。观察组不良反应发生率3.0%低于对照组的27.3%,差异具有统计学意义(P<0.05)。结论治疗消化性溃疡并急性上消化道出血时应用胃镜下注射治疗,可提高治疗效果,使患者血红蛋白含量升高,降低不良反应发生率。

Objective To discuss the clinical efficay of injection under gastroscope in the treatment of peptic ulcer complicated with acute upper gastrointestinal hemorrhage.Methods A total of 66 patients with peptic ulcer and acute upper gastrointestinal hemorrhage were randomly divided into control group and observation group according to random ball-touching method,with 33 cases in each group.The control group was treated with drug spraying on the lesion site under gastroscopy,and the observation group was treated with drug injection on the lesion site under gastroscope.Both groups were compared in terms of therapeutic effects,hemoglobin(Hb)levels before and after treatment,and the occurrence of adverse reactions.Results The total effective rate 97.0%in the observation group was higher than 66.7%in the control group,and the difference was statistically significant(P<0.05).After treatment,Hb(108.56±19.76)g/L in the observation group was higher than(96.17±15.88)g/L in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 3.0%in the observation group was lower than 27.3%in the control group,and the difference was statistically significant(P<0.05).Conclusion Injection under gastroscope in the treatment of peptic ulcer complicated with acute upper gastrointestinal hemorrhage can improve the therapeutic effect,increase the hemoglobin content and reduce the incidence of adverse reactions.