近视性屈光参差患者角膜塑形术后视觉相关生活质量及立体视功能的变化

Changes in vision-related QOL and stereoscopic function after orthokeratology in patients with myopic anisometropia

目的评估近视性屈光参差患者行角膜塑形镜矫正前后的视觉相关生活质量及立体视功能。方法回顾性系列病例研究,选取2015年3月至2019年3月因近视性屈光参差于湖州师范学院附属第一医院眼科就诊并行角膜塑形镜矫正的近视患者48例。采用25项美国国家眼科研究所视觉功能问卷调查(NEI-VFQ-25)中文版评估角膜塑形镜矫正前后患者的视觉相关生活质量。通过近立体视检查图本评估近视性屈光参差患者矫正前、矫正3个月后的立体视锐度。数据采用配对样本t检验及χ^(2)检验进行分析。结果近视性屈光参差患者行角膜塑形镜矫正3个月后的视觉相关生活质量,包括总体视觉情况、精神健康状态、近距离工作、远距离工作、驾驶和周边视野的评分均较配戴前显著提高,差异有统计学意义(P<0.01),但眼痛方面评分比矫正前明显降低,差异有统计学意义(P<0.01),而在一般健康状态、社交功能、社会角色限制、独立性和色觉方面矫正前后比较,差异均无统计学意义(P>0.05)。近视性屈光参差患者行角膜塑形镜矫正3个月后的近立体视功能优于矫正前,差异有统计学意义(χ^(2)=18.450,P<0.01)。结论配戴角膜塑形镜能够改善近视性屈光参差患者的视觉相关生活质量及立体视觉。

Objective To assess the vision-related quality of life(QOL)and stereoscopic function in patients with myopic anisometropia(MA)before and after correction with orthokeratology(Ortho-K)lens.Methods A total of 48 myopia patients who attended the Department of Ophthalmology in the First Affiliated Hospital of Huzhou University for MA and underwent correction with Ortho-K lens from March 2015 to March 2019 were selected for a retrospective case-series study.The Chinese version of the National Eye Institute 25-item Visual Function Questionnaire(NEI-VFQ-25)was used to assess the vision-related QOL of the patients before and after correction with Ortho-K lens.The stereoacuity of patients with MA before correction and after 3 months of correction was assessed by the near-stereoscopic examination diagram.Data were analyzed by paired sample t-test andχ^(2) test.Results The vision-related QOL,including overall visual condition,mental health status,near work,distance work,driving,and peripheral vision scores of patients with MA after 3 months of correction with Ortho-K lens were significantly higher than those before wearing,with statistically significant differences(P<0.01).However,the scores in eye pain were significantly lower than those before correction,with statistically significant difference(P<0.01).There were no statistically significant differences in general health status,social functioning,social role limitations,independence,and color vision before and after correction(P>0.05).The near-stereoscopic function of patients with MA was better after 3 months of correction with Ortho-K lens than that before correction,with statistically significant difference(χ^(2)=18.450,P<0.01).Conclusion Ortho-K lens can improve the vision-related QOL and stereopsis in patients with MA.