基于“真实世界”研究二甲硅油在肠镜检查前肠道准备时的应用效果

Study on the application effect of simethicone in bowel preparation before enteroscopy based on"real world"

目的基于"真实世界"研究二甲硅油在肠镜检查前肠道准备时的应用效果。方法选取2020年1年至12月在南京中医药大学第二附属医院/江苏省第二中医院肛肠科行肠镜检查的618例患者,按照肠道准备时是否采用二甲硅油分为试验组(n=369,磷酸钠盐+聚乙二醇电解质散+二甲硅油)和对照组(n=165,磷酸钠盐+聚乙二醇电解质散)。比较两组的肠道清洁度分级、肠道泡沫分级、Boston肠道准备量表(BBPS)评分。结果所有患者均完成肠道准备及肠镜检查。两组的肠道清洁度分级、肠道泡沫分级、BBPS评分比较,差异具有统计学意义(P<0.05)。结论肠镜检查前4 h采用二甲硅油行肠道准备,可减少肠道泡沫、提高肠道清洁度及BBPS评分,具有临床推广和应用价值。

Objective To study the application effect of simethicone in bowel preparation before enteroscopy based on"real world".Methods A total of 618 patients who underwent enteroscopy in the anorectal department of the second affiliated hospital of Nanjing university of Chinese medicine/the second middle school hospital of Jiangsu province from January to December 2020 were selected and divided into experimental group(n=369,sodium phosphate+polyethylene glycol electrolyte powder+simethicone)and control group(n=165,sodium phosphate+polyethylene glycol electrolyte powder)according to whether simethicone was used in bowel preparation.The intestinal cleanliness grading,intestinal foam grading and Boston bowel preparation scale(BBPS)score were compared between the two groups.Results All patients completed bowel preparation and enteroscopy.There were significant differences in intestinal cleanliness grading,intestinal foam grading and BBPS score between the two groups(P<0.05).Conclusion Bowel preparation with simethicone before 4 h of enteroscopy can reduce intestinal foam,improve intestinal cleanliness and BBPS score.It is worthy of clinical promotion and application.