基层医院应用地塞米松注射液预防瘢痕子宫择期剖宫产早期足月儿呼吸窘迫综合征的疗效观察

Effect of Dexamethasone Injection on Prevention of Respiratory Distress Syndrome in Early Term Infants of Elective Cesarean Section with Scar Uterus in Grass-roots Hospital

目的:探讨基层医院应用地塞米松注射液预防瘢痕子宫择期剖宫产早期足月儿呼吸窘迫综合征的疗效。方法:选取笔者所在医院2020年2月-2021年6月收治的280例瘢痕子宫择期剖宫产孕妇为研究对象,采用随机数字表法将其分为观察组与对照组,各140例。对照组在剖宫产前未进行地塞米松注射液治疗,观察组在剖宫产前48 h应用地塞米松注射液单疗程治疗。比较两组早期足月儿出生后呼吸窘迫综合征发生率、住院时间、肺炎发生率、转院率。结果:观察组早期足月儿出生后呼吸窘迫综合征发生率低于对照组,差异有统计学意义(P<0.05)。观察组早期足月儿住院时间短于对照组,差异有统计学意义(P<0.05)。观察组早期足月儿转院率低于对照组,差异有统计学意义(P<0.05)。观察组早期足月儿肺炎发生率低于对照组,但组间比较差异无统计学意义(P>0.05)。结论:基层医院应用地塞米松注射液可以降低瘢痕子宫择期剖宫产早期足月儿呼吸窘迫综合征发生率、患儿转院率,缩短住院时间,在临床上具有较高的研究价值。

Objective:To investigate the effect of Dexamethasone Injection on prevention of respiratory distress syndrome in early term infants of elective cesarean section with scar uterus in grass-roots hospital.Method:A total of 280 pregnant women with elective cesarean section with scar uterus who were admitted in our hospital from February 2020 to June 2021 were selected as the research objects.They were divided into the observation group and the control group by random number table method,with 140 cases in each group.The control group was not treated with Dexamethasone Injection before cesarean section,while the observation group was treated with Dexamethasone Injection in a single course 48 h before cesarean section.The incidence of post-natal respiratory distress syndrome,length of hospital stay,incidence of pneumonia and hospital transfer rate of early term infants were compared between the two groups.Result:The incidence of post-natal respiratory distress syndrome of early term infants in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The length of hospital stay of early term infants in the observation group was shorter than that in the control group,the difference was statistically significant(P<0.05).The hospital transfer rate of early term infants in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The incidence of pneumonia of early term infants in the observation group was lower than that in the control group,but there was no significant difference between the two groups(P>0.05).Conclusion:The application of Dexamethasone Injection in grass-roots hospital can reduce the incidence of respiratory distress syndrome in early term infants of elective cesarean section with scar uterus,and the hospital transfer rate of children,and shorten the length of hospital stay.It has high clinical research value.