曲安奈德联合康柏西普玻璃体腔注射对葡萄膜炎继发黄斑水肿患者视力的影响

Effects of intravitreal injection of triamcinolone acetonide combined with conbercept on vision in patients with uveitis secondary to macular edema

目的:探讨曲安奈德联合康柏西普玻璃体腔注射在葡萄膜炎继发黄斑水肿(UME)患者中的应用价值。方法:选取94例UME患者,将其随机分为对照组和观察组。对照组47例,予以曲安奈德玻璃体腔注射;观察组47例,加用康柏西普玻璃体腔注射,两组均连续治疗6个月。比较两组临床疗效、视力、并发症。结果:治疗后,观察组总有效率、最佳矫正视力(BCVA)高于对照组,视网膜厚度、并发症低于对照组,差异均有统计学意义(P<0.05)。结论:曲安奈德联合康柏西普玻璃体腔注射能够改善UME患者视力,降低并发症发生率,安全可靠,值得推广应用。

Objective:To investigate the application value of intravitreal injection of triamcinolone acetonide combined with conbercept in patients with uveitis secondary to macular edema(UME).Methods:A total of 94 UME patients were randomized into the observation group and control group,each with 47 cases.The control group received intravitreal injection of triamcinolone acetonide,while the observation group received intravitreal injection of the combined triamcinolone acetonide with conbercept.Both groups were treated for 6 months continuously.The clinical efficacy,visual acuity and complications were compared between the two groups.Results:The total effective rate of treatment and best corrected visual acuity(BCVA)in the observation group was higher than that in the control group,while the retinal thickness and incidence of complications in the observation group was lower than that in the control group,and the differences were statistically significant between both groups(P<0.05)Conclusion:The combination of triamcinolone acetonide and conbercept intravitreal injection can improve the vision of UME patients,reduce the incidence of complications,which is safe and reliable,and worthy of clinical application.