摘要
幽门螺杆菌(Helicobacter pylori,Hp)感染介导机体免疫应答,同时促进胃肠黏膜的自噬,两种途径都将影响肠道菌群。儿童Hp感染后根据其适应证,选择标准三联疗法进行根除治疗,但该疗法可能打破机体的微生态平衡。该文就儿童Hp感染与肠道菌群相关性及益生菌在Hp感染治疗中的作用作一综述。
Helicobacter pylori(Hp)infection mediates the immune response and promotes autophagy in gastrointestinal mucosa,both of which affect intestinal flora.According to the indications of Hp infection in children,the standard triple therapy is selected for the eradication treatment,but the treatment may break the microecological balance of the body.This article reviews the relationship between Hp infection and intestinal flora in children and the role of probiotics in the treatment of Hp infection.
作者
袁伟(综述)
黄永坤(审校)
Yuan Wei;Huang Yongkun(Department of Pediatrics,the First Affiliated Hospital,Kunming Medical University,Kunming 650032,China)
出处
《国际儿科学杂志》
2021年第10期671-675,共5页
International Journal of Pediatrics
关键词
儿童
幽门螺杆菌
肠道菌群
益生菌
Children
Helicobacter pylori
Intestinal flora
Probiotics
