俯卧位通气在急性呼吸窘迫综合征患者中的应用效果

Application of Prone Ventilation in Patients With Acute Respiratory Distress Syndrome

目的探讨俯卧位通气在急性呼吸窘迫综合征患者中的应用效果。方法2019年10月—2020年7月从医院ICU重症科室收治的急性呼吸窘迫综合征病例中随机抽取60例患者作为研究对象,根据随机数字表法将其分成两组,分别为研究组(n=30)和参照组(n=30),参照组患者治疗方式为常规体位通气,研究组患者治疗方式为俯卧位通气,对比分析不同组别下患者的各项临床指标、不良反应发生率以及血流动力学指标。结果两组患者在吸入氧浓度间对比差异无统计学意义(P>0.05),但研究无论是动脉血氧分压、气道痰液引流量还是脉搏血氧饱和度等指标均显著优于参照组,组间对比差异有统计学意义(P<0.05);研究组患者不良反应发生率为6.67%,参照组患者发不良反应发生率为30.00%,研究组不良反应发生率明显低于参照组,统计学对比差异有统计学意义(P<0.05);两组患者在HR、MAP、CVP以及CI等指标对比,经统计学对比分析差异无统计学意义(P>0.05),但研究组氧合指数明显低于参照组,统计学对比差异有统计学意义(P<0.05)。结论急性呼吸窘迫综合征患者在俯卧位通气治疗下的临床效果更好,不良反应症状少见。

Objective To investigate the effect of prone ventilation in patients with acute respiratory distress syndrome.Methods From October 2019 to July 2020,60 patients were randomly selected from the acute respiratory distress syndrome cases admitted to the ICU intensive care unit of the hospital as the research object,and they were divided into two groups according to the random number table method,which were the study group(n=30)and the reference group(n=30).The treatment mode of patients in the reference group was conventional position ventilation,and the treatment mode of patients in the study group was prone position ventilation.The clinical indicators,incidence of adverse reactions and hemodynamic indicators of patients in different groups were compared and analyzed.Results There was no statistically significant difference between the two groups in oxygen inhalation concentration(P>0.05).However,both arterial oxygen partial pressure,airway sputum drainage volume,pulse oxygen saturation and other indicators in the study were significantly better than those in the control group,and the difference between the two groups was statistically significant(P<0.05).The incidence of adverse reactions in the study group was 6.67%,and that in the reference group was 30.00%.The incidence of adverse reactions in the study group was significantly lower than that in the reference group,showing a statistically significant difference(P<0.05).There was no significant difference between the two groups in HR,MAP,CVP,CI and other indicators,and statistical comparison showed no significance(P>0.05).However,the oxygenation index of the study group was significantly lower than that of the reference group,with statistically significant difference(P<0.05).Conclusion Patients with acute respiratory distress syndrome have better clinical effect under prone position ventilation,adverse reactions are rare.