CT心肌灌注成像、ECV在OMI诊断中价值及与心肌损伤的关系

Diagnostic Value of CT Myocardial Perfusion Imaging and ECV in OMI and Their Relationship with Myocardial Injury

本研究探讨CT心肌灌注成像(CT-MPI)、细胞外容积(ECV)在陈旧性心肌梗死(OMI)诊断中的价值及与心肌损伤的相关性。选取82例OMI患者作为观察组,另选取同期健康者30例作为对照组,均行CT-MPI检查,对比两组CT-MPI参数、ECV,分析OMI发病影响因素及CT-MPI参数、ECV与心肌损伤指标的关系。结果显示,观察组cTnI、cTnT水平及ECV高于对照组,心肌血容量(MBV)、心肌血流量(MBF)低于对照组,且上述指标均为OMI发病影响因素(P<0.05);OMI患者MBF、MBV与cTnI、cTnT水平呈负相关,ECV与cTnI、cTnT水平呈正相关(P<0.05);MBF、MBV、ECV联合诊断OMI的ROC曲线下面积为0.950。CT-MPI参数MBF、MBV及ECV与OMI患者心肌损伤有关,CT-MPI参数、ECV检测可有效诊断OMI,利于临床诊治。

This study explored the value of CT myocardial perfusion imaging(CT-MPI)and extracellular volume(ECV)in the diagnosis of old myocardial infarction(OMI)and their correlation with myocardial injury.A total of 82 patients with OMI were selected as the observation group and 30 healthy subjects in the same period were selected as the control group.The CT-MPI parameters and ECV of the two groups were compared,the influencing factors of OMI and the relationship between CT-MPI parameters,ECV and myocardial injury indexes were analyzed,and the diagnostic value of CT-MPI parameters and ECV for OMI was evaluated.The levels of cTnI,cTnT and ECV in the observation group were higher than those in the control group,MBF and MBV were lower than those in the control group,and all indexes were the influencing factors of OMI(P<0.05);MBF and MBV were negatively correlated with cTnI and cTnT levels,while ECV was positively correlated with cTnI and cTnT levels(P<0.05).The maximum AUC of OMI diagnosed by MBF,MBV and ECV was 0.950.CT-MPI parameters MBF,MBV and ECV are related to myocardial injury in patients with OMI.The detection of CT-MPI parameters and ECV can effectively diagnose OMI and facilitate clinical diagnosis and treatment.