右美托咪定滴鼻预防舌系带矫正术儿童七氟烷全麻术后躁动的应用

Application of Dexmedetomidine Nasal Drops for Preventing Restlessness after Sevoflurane General Anesthesia in Children Undergoing Tongue Frenulum Correction

目的探讨右美托咪定滴鼻预防舌系带矫正术儿童七氟烷全麻术后躁动的效果。方法选取2018年12月至2020年12月于我院行舌系带矫正术的72例患儿,随机分为观察组与对照组各36例。对照组采用七氟烷全麻,观察组在对照组基础上采用右美托咪定滴鼻。比较两组的HR、MAP水平及苏醒时间、苏醒即刻PAED评分。结果麻醉30 min、术停即刻,两组的HR、MAP水平均高于麻醉前,且观察组的HR、MAP水平均低于对照组(P<0.05)。两组的苏醒时间比较差异无统计学意义(P>0.05)。观察组苏醒即刻PAED评分明显低于对照组(P<0.05)。结论右美托咪定滴鼻可维持舌系带矫正术七氟烷全麻患儿的血流动力学稳定,有效预防术后躁动发生。

Objective To explore the effect of dexmedetomidine nasal drops in preventing restlessness after sevoflurane general anesthesia in children undergoing tongue frenulum correction.Methods 72 children undergoing tongue frenulum correction in our hospital from December 2018 to December 2020 were selected and randomly divided into observation group and control group,with 36 cases in each group.The control group was given sevoflurane general anesthesia,and the observation group was given dexmedetomidine nasal drops on the basis of the control group.The HR and MAP levels,wake-up time and PAED score at wake-up immediately were compared between the two groups.Results 30 minutes after anesthesia and immediately after operation,the HR and MAP levels of the two groups were higher than those before anesthesia,and the HR and MAP levels of the observation group were lower than those of the control group(P<0.05).No statistical difference was found in the wake-up time between the two groups(P>0.05).The PAED score at wake-up immediately of the observation group was significantly lower than that of the control group(P<0.05).Conclusions Dexmedetomidine nasal drops can maintain stable hemodynamics in children undergoing tongue frenulum correction with sevoflurane general anesthesia,and effectively prevent postoperative restlessness.