摘要
HPV是一种嗜上皮性病毒,可通过性交、摩擦接触、自体种植等方式进行传播。HPV所引起的疾病与其病毒类型有关,低危型HPV主要引起皮肤良性赘生物"疣",而高危型HPV主要与各种癌症相关。人体感染HPV后,在无药物及其他医疗手段干预下病毒在体内的自然过程尚不明确。从感染结局分析,一部分HPV感染者能够将病毒清除而不导致疾病;一部分感染者体内的HPV成功逃避机体免疫细胞的杀伤,形成持续感染;持续感染的HPV可能在机体免疫力降低时出现相应疾病。本文对HPV感染人体后的自然过程的几种结局及特点进行综述,并对参考文献的可信度进行分析。
HPV is a kind of epitheliophilic virus,which can be transmitted by sexual intercourse,rubbing,or autologous implantation.Various diseases caused by HPV are related to its virus types.Low risk HPV mainly causes skin benign vegetative"warts",while high-risk HPV is mainly related to various cancers.After human beings infecting HPV,the natural histroy of the virus in the body is still not clear without intervention of drugs or other medical means.According to different outcomes of infection,some HPV infected people can remove the virus without causing disease;however another infected people have persistent infection due to HPV immune escape.Persistent infection of HPV may lead to corresponding diseases when the body’s immunity decreases.This paper reviews several outcomes and characteristics of natural histroy after HPV infection.And at the end of the article,we analyze the reliability of references.
作者
孙亚楠
齐蔓莉
SUN Yanan;QI Manli(Department of Dermatology,Tianjin Medical University General Hospital,Tianjin 300000,China)
出处
《皮肤科学通报》
2021年第5期451-458,M0007,共9页
Dermatology Bulletin
关键词
HPV感染
肛门生殖器癌症
疣
自然清除
持续感染
HPV infection
Anogenital cancer
Wart
Natural clearance
Persistent infection
