复方甘草酸苷佐治慢性荨麻疹的效果分析

Effect Analysis of Compound Licorice Glycosides in the Treatment of Chronic Urticaria

目的探讨复方甘草酸苷佐治慢性荨麻疹的效果。方法选择2018年4月—2020年1月沈阳友谊美容医院和北部战区总医院浑南医院收治的慢性荨麻疹患者70例,随机分为观察组和对照组各35例。对照组口服依巴斯汀治疗,观察组在对照组用药的基础上口服复方甘草酸苷治疗,4周后比较两组患者的疗效、临床症状消退时间和不良反应发生率。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05);观察组红斑消退时间、风团消退时间以及瘙痒缓解时间短于对照组,差异有统计学意义(P<0.05);两组间不良反应发生率比较,差异无统计学意义(P>0.05)。结论慢性荨麻疹患者在常规治疗基础上辅以复方甘草酸苷治疗疗效确切,安全可靠,值得临床进一步推广。

Objective To explore the effect of compound licorice glycoside in the treatment of chronic urticaria.Methods A total of 70 patients with chronic urticaria admitted to Shenyang Friendship Beauty Hospital and Hunnan Hospital of the Northern War Zone General Hospital from April 2018 to January 2020 were randomly divided into observation groups and control groups,35 cases in each group.The control group was treated with oral Ebastine,and the observation group was given oral compound licorice glycosides based on regimen of control group.The efficacy of the two groups,the time of clinical symptom resolution,as well as the incidence of adverse reactions were compared after 4 weeks.Results The total efficiency of the observation group significantly increased,and the time of erythema receding,the disappearance time of wheal,as well as the remission time of itch significantly decreased than the control group(P<0.05).The incidence of adverse reactions was similar between the two groups(P>0.05).Conclusion The addition of compound licorice glycoside to patient with chronic urticarial is safe and reliable on the basis of conventional treatment.