摘要
本研究采用前瞻性单臂试验的方法,选择自2018年2月至2020年6月在浙江金华广福医院接受放化疗的39例食管癌患者,男32例,女7例,年龄44-82(69±9)岁。用磁共振扩散加权成像(MR-DWI)检测患者治疗前后表观弥散系数(ADC)变化。结果显示治疗后ADC值较治疗前显著性升高[(2.03±0.42)×10^(-3)mm^(2)/s比(1.60±0.28)×10^(-3)mm^(2)/s],ADC值的升高程度与患者预后之间存在正相关性。
This study was a prospective single arm trial conducted in Zhejiang Jinhua Guangfu hospital from February 2018 to June 2020.A total of 39 patients(32 males and 7 females)with esophageal cancer,aged from 44 to 82(69±9)years were enrolled.Diffusion weighted magnetic resonance imaging(MR-DWI)was implemented to evaluate the changes of apparent diffusion coefficient(ADC)value before and after chemoradiotherapy.The results showed that the ADC value after chemoradiotherapy was higher than that before treatment[(2.03±0.42)×10^(-3)mm^(2)/s vs(1.60±0.28)×10^(-3)mm^(2)/s],and there was a positive correlation between the increase of ADC value and the prognosis of patients.
作者
张文宝
杨清波
吴双飞
陆绍华
程明
盛誉
张青春
杨柳飞
俞露
严森祥
Zhang Wenbao;Yang Qingbo;Wu Shuangfei;Lu Shaohua;Cheng Ming;Sheng Yu;Zhang Qingchun;Yang Liufei;Yu Luo;Yan Senxiang(Department of Radiotherapy,the First People′s Hospital of Jiande,Jiande 311600,China;Department of Radiology,Zhejiang Jinhua Guangfu Hospital,Jinhua 321000,China;Special Inspection Branch,Jinhua 5th Hospital,Jinhua 321000,China;Department of Thoracic Surgery,Zhejiang Jinhua Guangfu Hospital,Jinhua 321000,China;Department of Digestive Medicine,Zhejiang Jinhua Guangfu Hospital,Jinhua 321000,China;Department of Radiotherapy,the First Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 310003,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2021年第41期3427-3430,共4页
National Medical Journal of China
基金
金华市科技局公益类项目(2018-4-033)。
关键词
食管肿瘤
磁共振成像
表观扩散系数
放射治疗
Esophageal neoplasms
Magnetic resonance imaging
Apparent diffusion coefficient
Radiotherapy
