摘要
Lysosomes are the major degradative compartments within eukaryotic cells.Besides their role in the degradation and recycling of intra-and extracellular molecules,they further mediate important biological processes,such as immune signaling and perpetuation of nutrientand energy homeostasis.
基金
supported by the Interdisciplinary Center for Clinical Research(IZKF)at the University Hospital of the University of Erlangen-Nuremberg(JochenKalden funding programme N8)。