改编指南现状分析及研究前景

Current situation and research prospects of adaptation guidelines

目的分析国内外改编指南发表现状。方法计算机检索CBM、CNKI、VIP、WanFang Data、PubMed、EMbase、GIN、SIGN、NICE、AHRQ数据库,搜集国内外发表的改编指南研究,检索时限均为建库至2020年8月31日。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,描述性分析改编指南的发表现状。结果共纳入改编指南研究83篇,包括改编指南63篇、方法学研究16篇、二次研究4篇。改编指南发文数量整体呈上升趋势,48.39%发表在英国主办刊物。51.81%报告了在制订过程中受到基金或项目资助,67.46%报告了利益冲突信息。近五年发表的33篇改编指南中,33.34%报告改编方法学使用ADAPTE,6.1%报告改编方法学使用GRADE-Adolopment,60.56%未报告改编方法。结论目前国际已有多篇改编指南发表,但在我国尚处于起步阶段,改编指南需要依据理论框架,规范制订方法学,保证改编指南的质量。

Objective To analyze the current situation of adaptation guidelines.Methods CBM,CNKI,VIP,WanFang Data,PubMed,EMbase,GIN,SIGN,NICE and AHRQ databases were electronically searched to collect studies related to adaptation guidelines from inception to August 31 th,2020.Two reviewers independently screened literature,extracted data,and assessed the risk of bias of included studies.Descriptive analysis was then conducted on the general situation of the adaptation guidelines.Results A total of 83 studies were included,involving 63 full-text studies,16 methodological studies and 4 secondary studies.The quantity of published articles of the adapted guidelines had an overall upward trend,and 48.39%of the adapted guidelines were published in UK-hosted journals.51.81%of the adapted guidelines reported receiving funding or project funding during the development process,and 67.46%reported information of conflict of interests.Among the 33 adaptation guidelines published in the past five years,33.34%reported their methodology used ADAPTE,6.1%reported their methodology used GRADE-Adolopment,and 60.56%did not report the adaptation method.Conclusions At present,the international research on the adapted guideline is extensive,however,it is still in its infancy in China.The adaptation guideline is also required to be based on a theoretical framework,standardize the development of methodology,and ensure the quality of the adaptation guideline.