中医核心证候指标集的构建思路

Methods of developing core traditional Chinese medicine syndromes set

核心指标集的概念被引入中医领域以来,逐渐受到越来越多研究者的重视。研究者普遍认为,中医临床研究核心指标集应突出中医特色指标,如中医证候。但是目前核心指标集研究者对中医证候的关注不够,加上证候命名不规范,同一疾病的证候分类及诊断标准不一致,同一证候会出现在不同疾病中等问题,给研究带来困难。本研究基于前期研究,提出病证结合研究模式和以证统病模式下的中医核心证候指标集构建方法,以期为相关研究提供思路。

Since the concept of core outcome set(COS)was introduced into clinical trials of traditional Chinese medicine(TCM),researchers have paid much more attention to develop COS for specific diseases.Although researchers believe that the characteristics of TCM,such as syndromes,should be considered in the COS of TCM,it was insufficiently addressed.In addition,the naming of TCM syndromes has not been standardized,and the classification and diagnostic criteria for specific diseases have been inconsistent.Thus,it is difficult to include TCM syndromes in the COS.Different diseases may show similar TCM syndromes which makes research difficult.Based on previous studies,this paper provided methods of developing core TCM syndromes set according to the model of combination of disease and syndrome and the model of syndrome dominating disease to provide references for future researches.