红光照射在血液透析高磷患者中的应用效果

Application of red light irradiation on hemodialysis patients with hyperphosphatemia

目的探索体外红光照射对血液透析高磷患者的效果。方法采用便利取样法,选取60例血液透析高磷患者为研究对象,采用计算机随机数字发生器产生随机序列,将患者分为对照组、观察组,每组30例,对照组行常规血液透析,观察组则在血液透析过程中进行体外红光照射60分钟,光照10次为一个疗程,比较两组患者的血磷值、皮肤瘙痒评分、C反应蛋白含量、白细胞及血小板计数的差异。结果照光前与红光照射6次及10次后,观察组患者的血磷值及皮肤瘙痒评分均低于对照组,差异有统计学意义(P<0.05),但两组患者的C反应蛋白含量,白细胞及血小板计数比较时,无统计学意义(P>0.05)。结论血液透析过程中进行体外红光照射有利于降低高磷患者的血磷值,改善患者皮肤瘙痒症状,而且具有一定的安全性,但是对于C反应蛋白含量的升高有一定影响。

Objective to explore the effects of extracorporeal red light irradiation on c-reactive protein level,blood phosphorus level,skin pruritus score,leukocytes and platelets of hemodialysis patients with hyperphosphatemia.Methods 60 patients were selected as the subjects and computer random number generator was used to generate random sequence,which was randomly divided into control group and observation group,30 patients in each group.The control group received conventional hemodialysis,and the observation group received external red light irradiation for 60 min combined with conventional hemodialysis,10 times for a treatment course.Results There was obvious difference in blood phosphorus value and skin pruritus score after the sixth red light irradiation between the observation group and control group(P<0.05).Compared to the sixth red light irradiation,the blood phosphorus value in the observation group was significantly different from that in the observation group after the tenth red light irradiation(P<0.05).But there was no obvious difference in platelet levels,c-reactive protein and leukocyte between two groups.Conclusion Extranal red light irradiation during hemodialysis is profitable to reduce blood phosphorus value and skin pruritus.It is safe to use extranal red light irradiation for hemodialysis patients,but there is a certain effect on the increase of C-reactive protein value.