早产儿超声心脏几何形态学与血流动力学的相关性分析

Correlation Analysis of Ultrasound Cardiac Geometry and Hemodynamics in Premature Infants

目的:探讨与分析早产儿超声心脏几何形态学与血流动力学的相关性。方法:研究时间为2018年8月到2020年6月,选择本院收治的早产儿150例(早产组)和足月儿150例(足月组)作为研究对象,两组新生儿都给予超声检查,记录、左心室舒张期内径(Left ventricular diastolic diameter,LVDd)、左心室收缩期内径(Left ventricular systolic diastolic,LVDs)、左房内径(Left atrial diameter,LAD)、左心室相对厚度(Left ventricular relative wall thickness,LVRWT)、左心室心肌质量(Left ventricular myocardial mass,LVM)、左室后壁舒张期厚度(Left ventricular posterior walldepth,LVPWd)、左心室舒张末期容积(Left ventricular end diastolic volume,LVDV)、左心室收缩末期容积(Left ventricular end systolic volume,LVSV)、每搏输出量(Stroke volume,SV)、左心室射血分数(Left ventricular ejection fraction,LVEF)、左心室缩短分数(Left ventricular fractional shortening,LVFS)等指标并进行相关性分析。结果:早产组的LVDd、LVDs、LAD、LVPWd、LVRWT、LVM值都显著低于足月组(P<0.05)。早产组的LVDV、LVSV、SV值低于足月组(P<0.05),两组LVEF、LVFS值对比差异无统计学意义(P>0.05)。在早产组中,Pearson相关性分析显示LVDd、LVDs、LAD、LVPWd、LVRWT、LVM值与LVDV、LVSV、SV值存在正相关性(P<0.05)。Cox比例风险回归模型显示早产儿的出生体重、身长为影响LVDd、LVDV值的主要因素(P<0.05)。结论:早产儿超声心脏几何形态学指标与血流动力学指标呈正相关,提示超声能准确记录和监测早产儿的心脏几何形态学与血流动力学,可作为评估早产儿心功能的一种可靠方法。

Objective:To explore and analysis the correlation between ultrasound cardiac geometry and hemodynamics in premature infants.Methods:From August 2017 to June 2020.60 cases of premature infants(premature group)and 60 cases of term infants(term group)who were selected in our hospital were selected as the research objects.All the cases were given ultrasound examination,recorded cardiac geometric morphology,hemodynamic indicators(LVDd,LVDs,LAD,LVPWd,LVRWT,LVM and LVDV,LVSV,SV,LVEF,LVFS)and were given correlation analysis.Results:The LVDd,LVDs,LAD,LVPWd,LVRWT and LVM values of the preterm group were significantly lower than those of the term group(P<0.05).The LVDV,LVSV,and SV values of the preterm group were lower than those of the term group(P<0.05),and there were no significant difference in the LVEF and LVFS values compared between the two groups(P>0.05).In the preterm group,Pearson correlation analysis showed that LVDd,LVDs,LAD,LVPWd,LVRWT,LVM values were positively correlated with LVDV,LVSV,and SV values(P<0.05).The Cox proportional hazard regression model showed that the birth weight and length of premature infants were the main factors affected the LVDd and LVDV values(P<0.05).Conclusion:The ultrasound cardiac geometric morphology indexes and hemodynamic indexes of premature infants are positively correlated,suggesting ultrasound can accurately record and monitor the cardiac geometry and hemodynamics of premature infants,and they can be used as a reliable methods to evaluate the cardiac function of premature infants.