难治性便秘患儿症状与生活质量的相关性分析

Correlation Analysis between Symptoms and Quality of Life in Children with Refractory Constipation

目的:探讨难治性便秘患儿症状与生活质量的相关性。方法:选取2018年12月~2020年8月就诊于南京医科大学附属儿童医院消化科的450例功能性便秘患儿为研究对象,分为难治性便秘组(150例)及非难治性便秘组(300例),采用儿童生存质量测定量表(PedsQL4.0)评估其生活质量,并与150例健康体检儿童(健康对照组)比较。采用便秘症状评估表对难治性便秘患儿症状进行调查统计,分析难治性便秘患儿的症状与生活质量评分的相关性。结果:150例难治性便秘患儿出现较多的症状为:硬便148例(98.67%)、排便困难144例(96.00%)、排便频率减少(>3 d/次)117例(78.00%)。与非难治性便秘组比较,难治性便秘组的便秘症状6个条目得分与总分均明显增加(P<0.05)。与健康对照组比较,难治性便秘组和非难治性便秘组的生理功能、情感功能、社交功能、学校表现评分及总分均明显降低(P<0.05);与非难治性便秘组比较,难治性便秘组的生理功能、情感功能、社交功能、学校表现评分及总分均明显降低(P<0.05)。难治性便秘患儿便秘症状总分与情感功能、学校表现和生活质量总分呈负相关(P<0.05)。结论:难治性便秘患儿的生活质量下降,患儿便秘相关症状与生活质量密切相关。提示难治性便秘患儿治疗过程中,重视生理功能恢复的同时,还应当重视社会心理健康的恢复,从而改善患儿的生活质量。

Objective:To investigate the correlation between symptoms and quality of life in children with refractory constipation.Methods:A total of 450 children with functional constipation who were admitted to the gastroenterology department of Children’s Hospital Affiliated to Nanjing Medical University from December 2018 to August 2020 were selected as the research subjects,they were divided into the refractory constipation group(150 cases)and the non-refractory constipation group(300 cases),the pediatric quality of life inventory 4.0(PedsQL4.0)was used to assess their quality of life,and compared with 150 healthy children(healthy control group).The constipation symptom assessment questionnaire was used to investigate and count the symptoms of children with refractory constipation,and the correlation between the symptoms of children with refractory constipation and the quality of life score was analyzed.Results:150 children with refractory constipation had more symptoms:148 cases with hard stools(98.67%),144 cases with difficulty defecation(96.00%),and 117 cases with reduced defecation frequency(>3 d/time)(78.00%).Compared with the non-refractory constipation group,the scores of 6 items and total scores of constipation symptoms of the refractory constipation group were significantly higher(P<0.05).Compared with the healthy control group,the physiological function,emotional function,social function,school performance score and total score of the refractory constipation group and the non-refractory constipation group were significantly decreased(P<0.05).Compared with the non-refractory constipation group,the physiological function,emotional function,social function,school performance and total score of the refractory constipation group were significantly decreased(P<0.05).The total score of constipation symptoms in children with refractory constipation was negatively correlated with the total score of emotional function,school performance and quality of life(P<0.05).Conclusion:The quality of life of children with refractory constipation is decreased,and constipation-related symptoms are closely related to quality of life.It is suggested that in the treatment process of children with refractory constipation,attention should be paid not only to the recovery of physiological function,but also to the recovery of social and psychological health,so as to improve the quality of life of children.