血脂异常与动脉粥样硬化性泛血管疾病相关研究进展

Research progress on the association between dyslipidemia and atherosclerotic polyvascular diseases

动脉粥样硬化性泛血管疾病是指两个或两个以上动脉血管床发生动脉粥样硬化。近年来,从泛血管的角度系统认识血管性疾病并制订诊治策略逐渐受到重视。血脂异常作为动脉粥样硬化的危险因素,对动脉粥样硬化性泛血管疾病的发生、进展、严重程度及预后有不同程度的影响。更积极的降脂疗法对于泛血管疾病患者效果更佳、意义更深远。本文就动脉粥样硬化性泛血管疾病的发生风险与血脂异常的关系及泛血管疾病血脂管理现状和策略,对近年研究进展作一综述。

Atherosclerosis within two or more arterial beds has been termed polyvascular disease.In recent years,the systematic understanding of vascular diseases and the development of diagnosis and treatment strategies from the perspective of polyvascular medicine have gradually gained attention.Dyslipidemia,as a risk factor for atherosclerosis,has varying degrees of correlation with the occurrence,progression,severity and prognosis of polyvascular disease.More active lipid-lowering therapy is more effective and meaningful for patients with polyvascular disease.This paper reviews the role of dyslipidemia in polyvascular disease and the current status of blood lipid management in polyvascular disease,in order to provide a theoretical basis for further in-depth research and clinical application.