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乳腺癌合并原发性肺癌的临床分析:单中心10年的诊疗体会

Clinical analysis of surgical treatment of breast cancer with primary lung cancer:the experience of a single center for 10 years
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摘要 分析单中心诊治乳腺癌并发原发性肺癌患者的临床特点,为乳腺癌合并肺部第二原发癌的正确诊治提供参考。检索南方医科大学珠江医院自2008年1月—2017年12月因“乳腺癌”住院的患者病历,共1754例,其中56例乳腺癌患者并发肺部单发的实性占位性病变并进行了手术治疗,术后病理确诊为肺部原发性癌18例,归为肺原发癌组;确诊为乳腺癌肺转移38例,归为肺转移癌组。对比分析两组患者的临床资料。肺原发癌组所有患者均为女性,中位年龄为60.5(44.6~80.2)岁;18例患者肺癌病理均为腺癌,乳腺癌并发同侧原发性肺癌(14例)较并发对侧原发性肺癌(4例)更为多见。肺原发癌组6例患者进行了肺癌驱动基因检测,其中驱动基因突变阳性者3例,并且2例为非典型驱动基因突变。肺原发癌组与肺转移癌组相比较,发病与乳腺癌患者有无术后胸部放疗史相关(P<0.01)。乳腺癌并发肺部第二原发癌的患者并不少见,临床医师应该提高对多原发肿瘤的认识,为乳腺癌合并原发性肺癌的患者提供最佳的治疗方案。
作者 吴源周 陈群清 李辉 童健 张福伟 张健 WU Yuan-zhou;CHEN Qun-qing;LI Hui
出处 《中国现代普通外科进展》 CAS 2021年第11期910-913,共4页 Chinese Journal of Current Advances in General Surgery
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