补肾调肝汤对不孕症患者血清激素水平及妊娠的影响研究

The influences of the Bushen Tiaogan decoction on hormone level and pregnancy outcome of infertility patients

目的:研究补肾调肝汤对不孕症患者血清激素水平及妊娠的影响。方法:选取郴州市第一人民医院2016年4月-2018年4月92例不孕症患者,按照入院单双数法随机分为试验组和对照组(各46例)。对照组采取常规治疗,试验组在常规治疗的基础上加用补肾调肝汤治疗。比较两组患者的血清激素水平及妊娠情况。结果:治疗后,试验组的总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,试验组的中医证候积分较对照组低,差异具有统计学意义(P<0.05)。治疗后,试验组促黄体生成素(Luteinizing Hormone,LH)、卵泡刺激素(Follicle-Stimulating Hormone,FSH)较对照组低,雌二醇(Estradiol,E2)较对照组高(P<0.05)。治疗后,对两组患者进行为期6个月的电话跟踪随访,试验组妊娠率高于对照组(P<0.05)。结论:补肾调肝汤对治疗不孕症患者具有高效性、低不良反应的优势,可大大降低患者心理压力及经济负担,值得临床推广。

Objective:To study the effects of the Bushen Tiaogan decoction(补肾调肝汤)on serum hormone levels and pregnancy outcome of infertile patients.Methods:92 cases from April 2016 to April 2018 were selected and divided into the experimental group and the control group(46 cases in each)according to the odd and even number of admission.The control group took conventional treatment,and the experimental group was treated with the Bushen Tiaogan decoction more.Results:After treatment,the total efficiency in the experimental group was higher than that in the control group(P<0.05).The TCM syndrome score in the experimental group was lower than the control group(P<0.05).The LH and FSH in the experimental group were lower than the control group,and E2 was higher than the control group(P<0.05).After treatment,the patients in the groups were followed up by telephone for 6 months.The pregnancy in the experimental group was higher than the control group,and the difference was significant(P<0.05).Conclusion:The Bushen Tiaogan decoction has the advantages of high efficiency and low adverse reactions in the treatment of infertility,can greatly reduce the psychological pressure and economic burden of patients,and is worthy of clinical promotion.