新型冠状病毒肺炎疫情干预措施对惠州市结核病防控工作的影响

Impact of intervention measures for COVID-19 epidemic on tuberculosis prevention and control in Huizhou

目的了解新型冠状病毒肺炎疫情干预措施对广东省惠州市结核病防控工作的影响。方法通过《中国疾病预防控制信息系统》子系统《结核病信息管理系统》收集广东省惠州市2019年1—6月和2020年1—6月初诊肺结核患者登记信息、肺结核患者耐药筛查和治疗转归信息。通过惠州市基本公共卫生服务项目(结核病患者健康管理)报表,获取结核病患者督导访视和规则服药情况。根据我国新型冠状病毒肺炎疫情的实际状况,设定2020年1—6月为疫情期,设定2019年1—6月为基线期,比较疫情期间和基线期间惠州市肺结核患者发现、随访检查、服药管理和督导访视等的变化情况。结果新型冠状病毒肺炎疫情期间,惠州市肺结核患者检出率由基线期的26.32%(881/3347)上升到27.45%(794/2893),但差异无统计学意义(χ^(2)=0.997,P=0.318);病原学阳性肺结核患者耐药筛查率由基线期间的95.66%(375/392)上升到99.73%(372/373),差异有统计学意义(χ^(2)=13.771,P=0.000);确诊患者随访检查率由基线期间的96.37%(849/881)下降到96.10%(763/794),差异无统计学意义(χ^(2)=0.085,P=0.770);督导访视率由基线期的99.16%(8037/8105)上升到99.25%(7290/7345),差异无统计学意义(χ^(2)=0.529,P=0.397);规则服药率由基线期的95.46%(841/881)上升到96.10%(763/794),差异无统计学意义(χ^(2)=0.416,P=0.519)。结论新型冠状病毒肺炎疫情干预措施未对惠州市结核病防控工作造成影响,结核病防治服务体系运行良好,未来应该继续强化保障结核病服务体系,以确保在任何情况下都能提供正常的诊疗管理服务。

Objective To explore the influence of COVID-19 intervention measures on tuberculosis prevention and control in Huizhou,Guangdong Province. Methods The registration information,drug resistance screening and treatment outcome of tuberculosis patients in Huizhou,Guangdong from January to June in 2019 and2020 were collected through the Tuberculosis Management Information Systemin Chinese Disease Prevention and Control Information System.Tuberculosis patients’ supervision visits and regular medication were obtained through the Huizhou basic public health service project(tuberculosis patients’ health management)report.According to the actual situation of COVID-19 in China,January to June 2020 was set as the epidemic period and January to June2019 was set as the baseline period.The changes of discovery,follow-up examination,medication management and supervision visit of pulmonary tuberculosis patients in Huizhou during the two periods were compared.Results During the COVID-19 epidemic period,the detection rate of tuberculosis in Huizhou increased from26.32%(881/3347)to 27.45%(794/2893),but the difference was not statistically significant(χ^(2)=0.997,P=0.318);the screening rate of drug resistance in patients with pathogenic positive pulmonary tuberculosis increased from 95.66%(375/392)to 99.73%(372/373),the difference was statistically significant (χ^(2)=13.771,P=0.000);the follow-up examination rate of confirmed patients decreased from 96.37%(849/881)to 96.10%(763/794),the difference was not statistically significant (χ^(2)=0.085,P=0.770);the supervision visit rate increased from 99.16%(8037/8105)to 99.25%(7290/7345),the difference was not statistically significant(χ^(2)=0.529,P=0.397);the regular medication rate increased from 95.46%(841/881)to 96.10%(763/794),the difference was not statistically significant(χ^(2)=0.416,P=0.519). Conclusion The intervention measures for COVID-19 did not affect tuberculosis prevention and control in Huizhou,the tuberculosis prevention and control service system is running well.In the future,we should continue to strengthen the system to guarantee that the tuberculosis service system can provide normal diagnosis and treatment management services in any circumstance.