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麦角新碱联合缩宫素对产后出血产妇出血量与凝血功能水平的影响 被引量:3

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摘要 目的研究麦角新碱联合缩宫素对产后出血产妇出血量及凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、血浆纤维蛋白原(FIB)水平的影响。方法选取2019年1月至2020年6月邳州市人民医院收治的83例产后出血产妇,按照随机数字表法分为对照组(41例,采用缩宫素治疗)和观察组(42例,采用麦角新碱联合缩宫素治疗)。比较两组产妇产后30 min与1、2、24 h出血量,产后1、3、5 d子宫底下降幅度,产前、产后24 h凝血功能指标水平,产后24 h不良反应发生情况。结果产后30 min与1、2、24 h观察组产妇出血量少于对照组;产后1、3、5 d观察组产妇子宫底下降幅度大于对照组;与产前比,产后24 h两组产妇PT、APTT均缩短,且观察组短于对照组;与产前比,产后24 h两组产妇血浆FIB水平均降低,且观察组低于对照组;产后24 h观察组产妇不良反应总发生率为4.76%,低于对照组的29.27%(均P<0.05)。结论采用麦角新碱联合缩宫素治疗产后出血,可有效改善产妇产后凝血功能,减少产妇产后出血量,促进产妇产后子宫复旧,疗效显著,且安全性较高。
作者 谭芳芳
出处 《现代医学与健康研究电子杂志》 2021年第19期57-59,共3页 Modern Medicine and Health Research
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