2011-2017年沈阳市城区居民肝癌发病与死亡趋势分析

Trend analysis of incidence and mortality of liver cancer among residents in Shenyang urban area from 2011to 2017

目的分析沈阳市城区居民肝癌发病与死亡及变化趋势,为肝癌防治提供依据。方法分析沈阳市肿瘤发病登记处2011-2017年城区居民肝癌发病与死亡数据,计算粗发病率与粗死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、累积率、截缩率和年度变化百分比(annual percent change,APC)等指标。结果2011-2017年沈阳市城区居民肝癌发病6659例,粗发病率为25.32/10万,中标率为12.65/10万,世标率为12.53/10万,粗发病率APC为5.47%,0~64岁累积率为0.77%,0~74岁累积率为1.45%,35~64岁截缩率为22.85/10万;肝癌死亡5377例,粗死亡率为20.45/10万,中标率为10.14/10万,世标率为10.00/10万,粗死亡率APC为12.90%,0~64岁累积率为0.60%,0~74岁累积率为1.15%,35~64岁截缩率为17.63/10万。男性发病率与死亡率均高于女性(均P<0.05)。发病与死亡年龄高峰均为85+岁年龄组。结论沈阳市城区居民肝癌发病率和死亡率均呈现上升趋势,应将男性及高龄组人群作为重点干预对象,加强筛查并完善肝癌防治措施。

Objective To analyze the incidence and mortality of liver cancer among residents in Shenyang urban area from 2011 to 2017 and their trend,so as to provide the basis for the prevention and treatment of liver cancer.Methods The incidence and mortality data of liver cancer of residents in urban area from Shenyang Cancer Registry from 2011 to 2017 were analyzed.The crude incidence,the crude mortality,age-standardized incidence rate by Chinese standard population,age-standardized incidence rate by world standard population,cumulative rate,truncation rate and annual percent change(APC)were calculated.Results From 2011 to 2017,there were 6659 new cases of liver cancer registered in Shenyang urban area,with a crude incidence of liver cancer in Shenyang urban area of 25.32 per 100000,an age-standardized incidence rate by Chinese standard population of 12.65 per 100000,an age-standardized incidence rate by world standard population of 12.53 per 100000,and an APC of crude incidence of 5.47%.The cumulative rate of 0~64 years old was 0.77%,the cumulative rate of 0~74 years old was 1.45%,and the truncation rate of 35~64 years old was 22.85 per 100000.There were 5377 death cases of liver cancer registered in Shenyang urban area,with a crude mortality of liver cancer in Shenyang urban area of 20.45 per 100000,an age-standardized mortality rate by Chinese standard population of 10.14 per 100000,an age-standardized mortality rate by world standard population of 10.00 per 100000,and an APC of crude mortality of 12.90%.The cumulative rate of 0~64 years old was 0.60%,the cumulative rate of 0~74 years old was 1.15%,and the truncation rate of 35~64 years old was 17.63 per 100000.The incidence and mortality of males were higher than those of females.The onset age peak of incidence and mortality was 85+years old.Conclusions The incidence and mortality of liver cancer among residents in Shenyang urban area showed an increasing trend.It is necessary to focus on the intervention of males and the elderly,strengthen screening and improve the prevention and treatment measures of liver cancer.