摘要
Cupping therapy is one of the most ancient traditional and complementary medicine practices that using globally by many civilizations. This protocol is setting the methods for conducting a new comprehensive systematic review to evaluate and set recommendations regarding safety of cupping therapy practice. Randomized clinical trials, case series, and case studies will be selected to be included in this study. PubMed, Trip medical database, and Cochrane Library be searched Since inception to 1 December 2021. The main outcomes of the systematic review will be: details of adverse events, casualty of identified adverse events (WHO-UMC causality scale) and severity of adverse events (Common Terminology Criteria (CTCAE) scale). Assessment of quality of reporting of safety in randomized clinical trials will be done. Classification of adverse events related to cupping therapy, recommendations regarding safety and suggestions regarding future cupping therapy research will be provided in the full-text of the systematic review. Highlights-The first comprehensive systematic review protocol of adverse events related to cupping therapy. There is no time or geographic location limits for selection of studies. The systematic review will give full evaluation of safety of cupping therapy.
