黑水虻抗菌肽的研究进展

Research advances on antibacterial peptides from Hermetia illucens

黑水虻是近几年昆虫资源研究领域的热点,目前其应用研究主要集中在饲料添加剂和有机垃圾处理等方面。然而,近年来研究发现,黑水虻幼虫自身免疫系统产生的抗菌肽对革兰氏阴性菌、革兰氏阳性菌以及真菌都具有广谱抗菌活性,有着广泛的应用前景。为了促进黑水虻抗菌肽的开发和应用,本文主要综述了黑水虻抗菌肽的结构特征、抑菌活性、作用机制、生产制备和应用实践,为黑水虻高附加值产品的开发和产业化提供理论依据和数据支持。

Hermetia illucens has become one of the most promising species in the insect resources research field,which is commonly used in feed additives process and organic waste treatment area.In recent years,it is found that antibacterial peptides produced by Hermetia illucens immune system have prospective application values due to the broad-spectrum antibacterial activity against many kinds of microorganisms,including gram-negative bacteria,gram-positive bacteria and fungi.In order to improve the development and application of antibacterial peptides from Hermetia illucens,the molecular structure,antibacterial activity and mechanism,production preparation and application prospect were summarized in this paper,which may provide theoretical support and novel idea for the development and industrialization of high value-added products produced by Hermetia illucens.