摘要
目的探讨新型冠状病毒肺炎疫情期间社会及医院采取一级响应防控措施后,以高压氧治疗为主的住院患者发生医院感染(HAI)的状况。方法统计新型冠状病毒肺炎疫情一级响应措施结束后南京紫金医院2020年2月接受高压氧治疗的住院患者(观察组,138例)的HAI发生率和感染病原学检查结果,并与2019年2月(同比对照,133例)和2019年12月(环比对照,213例)接受高压氧治疗的住院患者的相应指标进行对比分析。结果观察组患者的HAI发生率为10.87%(15/138),较同比对照组的15.04%(20/133)和环比对照组的15.02%(32/213)均下降了约5%,但差异无统计学意义(χ^(2)=1.43,P=0.49)。观察组检出的病原菌为铜绿假单胞菌、鲍曼不动杆菌和黏质沙雷菌,较环比对照组检出的菌种有所减少。结论严格的社交隔离和病房感染控制措施有降低以高压氧治疗为主的住院患者HAI发生率的趋势,但结果有待多中心大样本数据进一步论证。
Objective To investigate hospital acquired infection(HAI)in hospitalized patients who were mainly treated with hyperbaric oxygen(HBO)during the period when the whole society and the hospital were in level one public health emergency response to COVID-19.Methods The HAI incidence and infectious pathogen test results of 138 patients(the observation group)who were given HBO therapy in Nanjing Zijin Hospital in February 2020,the period of level one public health emergency response to COVID-19,were collected,and they were analyzed in year-on-year comparison with the corresponding data of the 133 patients(the control group I)admitted to the hospital in February 2019,and in month-on-month comparison with the corresponding data of the 213 patients(the control group II)admitted to the hospital in December 2019.Results The HAI incidence of the observation group(10.87%)was about 5%lower than that(15.04%)in the control group I and that(15.02%)in the control group II,but there was no statistical difference(χ^(2)=1.43,P=0.49).The pathogens detected in the observation group were pseudomonas aeruginosa,acinetobacter baumannii,and serratia marcescens,which were less than those detected in the control group II.Conclusion Strict social isolation and ward infection control measures can effectively reduce HAI incidence in patients given HBO therapy,but the reliability of such measures needs further demonstration by multi-center and large-sample data.
作者
王国兴
李银芝
李敏
王霞
潘兴明
高志强
Wang Guoxing;Li Yinzhi;Li Min;Wang Xia;Pan Xingming;Gao Zhiqiang(Hyperbaric Oxygen Department,Nanjing Zijin Hospital,Nanjing 211100,China)
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2021年第5期656-658,共3页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
新型冠状病毒肺炎
医院感染
高压氧
COVID-19
Hospital acquired infections
Hyperbaric oxygen