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艾灸联合多磺酸粘多糖乳膏防治血液透析动静脉内瘘功能障碍临床研究 被引量:4

Clinical Study on Moxibustion Combined with Mucopolysaccharide Polysulfate Cream in Prophylaxis and Therapy for Arteriovenous Fistula Dysfunction of Patients with Hemodialysis
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摘要 目的:观察艾灸联合多磺酸粘多糖乳膏防治血液透析动静脉内瘘功能障碍的临床疗效。方法:选择80例行血液透析治疗的自体动静脉内瘘患者,采用随机数字表法分为观察组和对照组各40例。对照组实施常规血液透析治疗,观察组在对照组基础上给予艾灸联合多磺酸粘多糖乳膏外涂。比较2组治疗前后内瘘功能、血液流变学指标及血小板功能,记录2组血管相关并发症发生率。结果:治疗前,2组内瘘功能指标比较,差异无统计学意义(P>0.05)。治疗后,2组内瘘血流量、透析中血流量、内瘘内径较治疗前降低,动脉端压力、静脉端压力较治疗前升高;观察组内瘘血流量、透析中血流量、内瘘内径高于对照组,动脉端压力、静脉端压力低于对照组;差异均有统计学意义(P<0.05)。治疗前,2组血液流变学指标及血小板指标比较,差异无统计学意义(P>0.05)。治疗后,2组红细胞压积、血浆黏度、纤维蛋白原、血小板聚集率较治疗前降低,且观察组各项指标均低于对照组(P<0.05)。观察组血管并发症发生率为5.00%,低于对照组20.00%,差异有统计学意义(P<0.05)。结论:艾灸联合多磺酸粘多糖乳膏在血液透析动静脉内瘘功能障碍中的应用效果良好,可有效保护内瘘功能,改善局部血液循环,维持血液透析质量。 Objective:To observe the clinical effect of moxibustion combined with mucopolysaccharide polysulfate cream in prophylaxis and therapy for arteriovenous fistula dysfunction of patients with hemodialysis.Methods:A total of 80 cases of patients who received hemodialysis and had autologous arteriovenous fistula were randomly divided into the observation group and the control group according to the random number table method,with 40 cases in each group.The control group was treated with routine hemodialysis,and the observation group was additionally treated with moxibustion combined with external application of mucopolysaccharide polysulfate cream based on the treatment of the control group.Before and after treatment,the fistula function,hemorheology indexes and platelet function in the two groups were compared,and the incidence of vascular complications was recorded.Results:Before treatment,there was no significant difference being found in the comparison of fistula function values between the two groups(P>0.05).After treatment,the blood flow in internal fistula,blood flow during dialysis and diameters of internal fistula in the two groups were decreased when compared with those before treatment,and the arterial end pressure and venous end pressure were increased;the blood flow in internal fistula,blood flow during dialysis and internal fistula diameter in the observation group were higher than those in the control group,and the arterial end pressure and venous end pressure in the observation group were lower,differences being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of values of hemorheology and platelet between the two groups(P>0.05).After treatment,hematocrit,plasma viscosity,fibrinogen and platelet aggregation rate in the two groups were decreased when compared with those before treatment,and the values in the observation group were lower than those in the control group(P<0.05).The incidence of vascular complications in the observation group was 5.00%,lower than that of 20.00%in the control group,the difference being significant(P<0.05).Conclusion:The application of moxibustion combined with mucopolysaccharide polysulfate cream has an obvious effect in the treatment of patients underwent hemodialysis and with arteriovenous fistula dysfunction,which can effectively protect the fistula function,improve local blood circulation and maintain the quality of hemodialysis.
作者 李悦悦 LI Yueyue
出处 《新中医》 CAS 2021年第21期206-209,共4页 New Chinese Medicine
基金 温州市基础性科研项目(2019Y0750)。
关键词 血液透析 动静脉内瘘 功能障碍 艾灸 多磺酸粘多糖乳膏 血液流变学 血小板 血管相关并发症 Hemodialysis Arteriovenous fistula Dysfunction Moxibustion Mucopolysaccharide polysulfate cream Hemorheology Platelet Vascular complications
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