妊娠期甲状腺功能亢进危象的预警

Early warning of thyroid storm during pregnancy

甲状腺功能亢进(甲亢)危象是一种内分泌急症,其特点是病情常迅速恶化。妊娠合并甲亢危象发生率低、病死率高,因此给临床诊治带来极大挑战。多数甲亢危象的发生存在明确的诱因,诊断多依靠临床表现。目前,甲亢危象的诊断标准有几种预测模型,但各有利弊,在临床工作中需要综合分析,力求早期及时诊断,并尽快启动准确、有效的治疗,避免不恰当用药,改善围产结局。

Thyroid storm is a kind of endocrine emergency,which is characterized by rapid deterioration.Pregnancy with thyroid storm has the characteristics of low incidence and high mortality,which brings great challenge to clinical diagnosis and treatment.The occurrence of thyroid storm has clear incentives,and the diagnosis is mostly based on clinical manifestations.At present,there are several predictive models for the diagnosis of thyroid storm,but each has its advantages and disadvantages.In clinical work,a comprehensive analysis is required to strive for early and timely diagnosis,and to initiate accurate and effective treatment as soon as possible and avoid inappropriate medication,in order to improve perinatal outcome.