骨瓣开颅显微镜手术与神经外科锁孔手术治疗颅内肿瘤患者的效果比较

Comparison of effects between bone flap craniotomy microscopic surgery and neurologic surgical key hole operation in the treatment of patients with intracranial tumor

目的比较骨瓣开颅显微镜手术与神经外科锁孔手术治疗颅内肿瘤患者的效果,以期为临床手术方式的选择提供参考。方法选取2019年1月至2020年12月于我院行手术治疗的60例颅内肿瘤患者作为研究对象,根据手术方式不同将其分为对照组和观察组,各30例。对照组采用骨瓣开颅显微镜手术治疗,观察组采用神经外科锁孔手术治疗。比较两组的神经元特异性烯醇化酶(NSE)、中枢神经特异蛋白(S100β)水平、临床疗效及术后并发症发生情况。结果对照组术后15 min的NSE、S100β水平高于术前和观察组,差异具有统计学意义(P<0.05);观察组术前与术后15 min的NSE、S100β水平比较,差异无统计学意义(P>0.05)。观察组的治疗总有效率为93.33%,高于对照组的73.33%,差异具有统计学意义(P<0.05)。观察组的术后并发症总发生率为10.00%,低于对照组的30.00%,差异具有统计学意义(P<0.05)。结论相较于骨瓣开颅显微镜手术,神经外科锁孔手术治疗颅内肿瘤患者的效果更好,对神经的损伤更小,术后并发症总发生率更低,更利于患者恢复。

Objective To compare the effects of bone flap craniotomy microscopic surgery and neurologic surgical key hole operation in the treatment of patients with intracranial tumor,so as to provide reference for the selection of clinical operation methods.Methods A total of 60 patients with intracranial tumor who underwent surgery in our hospital from January 2019 to December 2020 were selected as the research objects.The patients were divided into control group and observation group according to different operation methods,with 30 cases in each group.The control group was treated with bone flap craniotomy microscopic surgery,and the observation group was treated with neurologic surgical key hole operation.The neuron specific enolase(NSE),central nerve specific protein(S100β)levels,clinical efficacy and occurrence of postoperative complications were compared between the two groups.Results The NSE and S100βlevels in the control group at 15 min after operation were significantly higher than those before operation and the observation group,and the differences were statistically significant(P<0.05);there were no differences in the NSE and S100βlevels before and 15 min after operation in the observation group(P>0.05).The total effective rate of treatment in the observation group was 93.33%,which was higher than 73.33%in the control group,and the difference was statistically significant(P<0.05).The total incidence of postoperative complications in the observation group was 10.00%,which was lower than 30.00%in the control group,and the difference was statistically significant(P<0.05)Conclusion Compared with bone flap craniotomy microscopic surgery,neurologic surgical key hole operation in the treatment of patients with intracranial tumor has better effect,with less nerve damage,lower total incidence of postoperative complications and more conducive to the recovery of patients.