麻蚣清金宁哮方联合布地奈德治疗小儿热性哮喘的效果

Effect of Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma

目的探究麻蚣清金宁哮方联合布地奈德治疗小儿热性哮喘的效果及对中性粒细胞百分比(NEUT%)、C反应蛋白(CRP)、嗜酸性粒细胞(EOS)和嗜碱性粒细胞(BASO)的影响。方法选取2020年7月至2021年2月济南市中医医院儿科门诊收治的热性哮喘患儿120例作为研究对象,采用随机数字表法将其分为A组(60例)和B组(60例)。A组给予布地奈德吸入治疗,B组在A组的基础上给予麻蚣清金宁哮方口服治疗。治疗1周后评价两组临床疗效,观察两组患儿治疗前后血清NEUT%、CRP、EOS和BASO的浓度变化。结果治疗后,B组总有效率高于A组(P<0.05)。治疗后,两组血清NEUT%、CRP、EOS、BASO浓度均较治疗前降低(P<0.05),且B组低于A组(P<0.05)。结论麻蚣清金宁哮方联合布地奈德治疗小儿热性哮喘能明显改善气道炎症,提高免疫功能。

Objective To explore the therapeutic effect of Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma and its effect on the percentage of neutrophils(NEUT%),C-reactive protein(CRP),eosinophils(EOS),and basophils(BASO).Methods A total of 120 child patients in the Pediatric Outpatient Department of Jinan Hospital of Traditional Chinese Medicine from July 2020 to February 2021 were selected as the research subjects,and they were divided into group A(60 cases)and group B(60 cases)by random number table method.Group A was treated with Budesonide inhalation.On the basis of group A,group B was given oral treatment of Magong Qingjin Ningxiao Formula.After treatment for one week,the clinical efficacy in both groups was evaluated,and the serum NEUT%,EOS,and BASO concentration variations of the two groups before and after treatment were observed.Results After treatment,the total effective rate of group B was higher than that in group A(P<0.05).After treatment,the serum NEUT%,CRP,EOS,and BASO concentrations in two groups were lower than those before treatment(P<0.05),which in the group B were lower than those in the group A(P<0.05).Conclusion Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma can significantly improve airway inflammation and enhance immune function.