摘要
Recent advances in the desilylative acylation of 1-alkenylsilanes with acid anhydrides under transition metal catalysis are summarized.This catalytic desilylative acylation of 1-alkenylsilanes provides an efficient route toα,β-unsaturated ketones by using rhodium or iridium as the catalyst.Moreover,various one pot sequence reactions have been developed,which can synthesizeα,β-unsaturated ketones from simple starting materials in an economic way.Additionally,this approach is applied to the asymmetric synthesis of atropisomers possessing silanol groups with excellent enantioselectivity.
基金
Financial support from National Natural Science Foundation of China(No.21871053)
the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(No.2019R01005)
the Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(No.2020ZD04)。
